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Human Adenosine A2A Receptor: Molecular Mechanism of Ligand Binding and Activation

Frontiers in pharmacology, 2017-12, Vol.8, p.898-898

2017

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Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

Nature (London), 2011-05, Vol.474 (7352), p.521-525

2011

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Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region

Nature (London), 2016-08, Vol.536 (7617), p.484-487

2016

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Steering G protein activation by mGlu heterodimer

Cell research, 2023-10, Vol.33 (10), p.735-736

Lebon, Guillaume

2023

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Thermostabilisation of an Agonist-Bound Conformation of the Human Adenosine A2A Receptor

Journal of molecular biology, 2011-06, Vol.409 (3), p.298-310

2011

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A mutagenesis and screening strategy to generate optimally thermostabilized membrane proteins for structural studies

Nature protocols, 2016-08, Vol.11 (8), p.1554-1571

2016

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Fine-tuning receptor–G protein activation and signaling

Science (American Association for the Advancement of Science), 2020-07, Vol.369 (6503), p.507-508

Lebon, Guillaume

2020

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Development and validation of a mass spectrometry binding assay for mGlu5 receptor

Analytical and bioanalytical chemistry, 2020-09, Vol.412 (22), p.5525-5535

2020

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Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and Gs

Scientific reports, 2018-03, Vol.8 (1), p.1-13, Article 4407

2018

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Outrunning free radicals in room-temperature macromolecular crystallography

Acta crystallographica. Section D, Biological crystallography., 2012-07, Vol.68 (7), p.810-818

2012

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A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone

Toxins, 2017-07, Vol.9 (7), p.227

2017

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Mutagenic Mapping Suggests a Novel Binding Mode for Selective Agonists of M1 Muscarinic Acetylcholine Receptors

Molecular pharmacology, 2009-02, Vol.75 (2), p.331-341

2009

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Observations des usages et nouveaux usages des bancs publics : comment redonner toute sa place au vivre ensemble dans les centres-villes ? L’exemple de la ville de Caen

La Revue du MAUSS semestrielle, 2019-10, Vol.54 (2), p.229-242, Article 229-242

Lebon, Guillaume

2019

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Molecular signatures of G-protein-coupled receptors

Nature (London), 2013-02, Vol.494 (7436), p.185-194

2013

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Molecular Determinants of CGS21680 Binding to the Human Adenosine A2A Receptor

Molecular pharmacology, 2015-06, Vol.87 (6), p.907-915

2015

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Human Adenosine A 2A Receptor: Molecular Mechanism of Ligand Binding and Activation

Frontiers in pharmacology, 2017, Vol.8, p.898

2017

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Thermostabilisation of an agonist-bound conformation of the human adenosine A(2A) receptor

Journal of molecular biology, 2011-06, Vol.409 (3), p.298

2011

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Agonist-bound structures of G protein-coupled receptors

Current opinion in structural biology, 2012-08, Vol.22 (4), p.482-490

2012

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Piezo1 is required for outflow tract and aortic valve development

Journal of molecular and cellular cardiology, 2020-06, Vol.143, p.51-62

2020

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Optical Control of Adenosine A 2A Receptor Using Istradefylline Photosensitivity

ACS chemical neuroscience, 2024-02, Vol.15 (3), p.645-655

2024

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Mycolactone: The amazing analgesic mycobacterial toxin

Toxicon (Oxford), 2018-07, Vol.149, p.88-88

2018

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Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5

ACS chemical biology, 2022-10, Vol.17 (10), p.2744-2752

2022

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Optical Control of Adenosine A2A Receptor Using Istradefylline Photosensitivity

ACS chemical neuroscience, 2024-02, Vol.15 (3), p.645-655

2024

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Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations

Cell reports (Cambridge), 2021-08, Vol.36 (9), p.109648-109648, Article 109648

2021

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Inhibition of the angiotensin II type 2 receptor AT2R is a novel therapeutic strategy for glioblastoma

Proceedings of the National Academy of Sciences - PNAS, 2022-08, Vol.119 (32)

2022

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Human Adenosine A2A Receptor: Molecular Mechanism of Ligand Binding and Activation

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region

Steering G protein activation by mGlu heterodimer

Thermostabilisation of an Agonist-Bound Conformation of the Human Adenosine A2A Receptor

A mutagenesis and screening strategy to generate optimally thermostabilized membrane proteins for structural studies

Fine-tuning receptor–G protein activation and signaling

Development and validation of a mass spectrometry binding assay for mGlu5 receptor

Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and Gs

Outrunning free radicals in room-temperature macromolecular crystallography

A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone

Mutagenic Mapping Suggests a Novel Binding Mode for Selective Agonists of M1 Muscarinic Acetylcholine Receptors

Observations des usages et nouveaux usages des bancs publics : comment redonner toute sa place au vivre ensemble dans les centres-villes ? L’exemple de la ville de Caen

Molecular signatures of G-protein-coupled receptors

Molecular Determinants of CGS21680 Binding to the Human Adenosine A2A Receptor

Human Adenosine A 2A Receptor: Molecular Mechanism of Ligand Binding and Activation

Thermostabilisation of an agonist-bound conformation of the human adenosine A(2A) receptor

Agonist-bound structures of G protein-coupled receptors

Piezo1 is required for outflow tract and aortic valve development

Optical Control of Adenosine A 2A Receptor Using Istradefylline Photosensitivity

Mycolactone: The amazing analgesic mycobacterial toxin

Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5

Optical Control of Adenosine A2A Receptor Using Istradefylline Photosensitivity

Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations

Inhibition of the angiotensin II type 2 receptor AT2R is a novel therapeutic strategy for glioblastoma

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