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Polymer-drug conjugate therapeutics: advances, insights and prospects

Nature reviews. Drug discovery, 2019-04, Vol.18 (4), p.273-294

2019

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Local Cancer Recurrence: The Realities, Challenges, and Opportunities for New Therapies

CA: a cancer journal for clinicians, 2018-11, Vol.68 (6), p.488-505

2018

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Biologically Responsive Polymeric Nanoparticles for Drug Delivery

Advanced materials (Weinheim), 2012-07, Vol.24 (28), p.3878-3886

2012

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Microscopy and tunable resistive pulse sensing characterization of the swelling of pH-responsive, polymeric expansile nanoparticles

Nanoscale, 2013-04, Vol.5 (8), p.3496-3504

2013

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Local drug delivery strategies for cancer treatment: Gels, nanoparticles, polymeric films, rods, and wafers

Journal of controlled release, 2012-04, Vol.159 (1), p.14-26

2012

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Prevention of nodal metastases in breast cancer following the lymphatic migration of paclitaxel-loaded expansile nanoparticles

Biomaterials, 2013-02, Vol.34 (7), p.1810-1819

2013

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Boolean logic in synthetic biology and biomaterials: Towards living materials in mammalian cell therapeutics

Clinical and translational medicine, 2023-07, Vol.13 (7), p.e1244-n/a

2023

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The performance of expansile nanoparticles in a murine model of peritoneal carcinomatosis

Biomaterials, 2011-01, Vol.32 (3), p.832-840

2011

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Nanoparticle Migration and Delivery of Paclitaxel to Regional Lymph Nodes in a Large Animal Model

Journal of the American College of Surgeons, 2012-03, Vol.214 (3), p.328-337

2012

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Paclitaxel-Loaded Expansile Nanoparticles Delay Local Recurrence in a Heterotopic Murine Non-Small Cell Lung Cancer Model

The Annals of thoracic surgery, 2011-04, Vol.91 (4), p.1077-1084

2011

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Ultra-high drug loading improves nanoparticle efficacy against peritoneal mesothelioma

Biomaterials, 2022-06, Vol.285, p.121534, Article 121534

2022

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Immunotherapies for locally aggressive cancers

Advanced drug delivery reviews, 2024-07, Vol.210, p.115331, Article 115331

2024

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Radiolabeled Biodistribution of Expansile Nanoparticles: Intraperitoneal Administration Results in Tumor Specific Accumulation

ACS nano, 2023-02, Vol.17 (3), p.2212-2221

2023

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Highly Specific and Sensitive Fluorescent Nanoprobes for Image-Guided Resection of Sub-Millimeter Peritoneal Tumors

ACS nano, 2017-02, Vol.11 (2), p.1466-1477

2017

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Pilot-scale production of expansile nanoparticles: Practical methods for clinical scale-up

Journal of controlled release, 2021-09, Vol.337, p.144-154

2021

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Tumor Targeted Nanoparticles: A Modern Day Trojan Horse

Seminars in thoracic and cardiovascular surgery, 2011, Vol.23 (1), p.10-11

2011

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Nanotechnology applications in thoracic surgery

European journal of cardio-thoracic surgery, 2016-07, Vol.50 (1), p.6-16

2016

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Ease of Synthesis, Controllable Sizes, and In Vivo Large-Animal-Lymph Migration of Polymeric Nanoparticles

ChemMedChem, 2010-09, Vol.5 (9), p.1435-1438

2010

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In Vitro Activity of Paclitaxel-Loaded Polymeric Expansile Nanoparticles in Breast Cancer Cells

Biomacromolecules, 2013-06, Vol.14 (6), p.2074-2082

2013

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Synthesis of poly(1,2-glycerol carbonate)-paclitaxel conjugates and their utility as a single high-dose replacement for multi-dose treatment regimens in peritoneal cancer

Chemical science (Cambridge), 2017-12, Vol.8 (12), p.8443-8450

2017

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Nanoparticle drug‐delivery systems for peritoneal cancers: a case study of the design, characterization and development of the expansile nanoparticle

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 2017-05, Vol.9 (3), p.n/a

2017

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Reinforcement of polymeric nanoassemblies for ultra-high drug loadings, modulation of stiffness and release kinetics, and sustained therapeutic efficacy

Nanoscale, 2018-05, Vol.10 (18), p.8360-8366

2018

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Two-Step Delivery: Exploiting the Partition Coefficient Concept to Increase Intratumoral Paclitaxel Concentrations In vivo Using Responsive Nanoparticles

Scientific reports, 2016-01, Vol.6 (1), p.18720-18720, Article 18720

2016

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Evaluation of expansile nanoparticle tumor localization and efficacy in a cancer stem cell-derived model of pancreatic peritoneal carcinomatosis

Nanomedicine (London, England), 2016-05, Vol.11 (9), p.1001-1015

2016

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Paclitaxel-Eluting Polymer Film Reduces Locoregional Recurrence and Improves Survival in a Recurrent Sarcoma Model: A Novel Investigational Therapy

Annals of surgical oncology, 2012, Vol.19 (1), p.199-206

2012

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Chemistry
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Drug Delivery Systems
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Paclitaxel - Administration & Dosage
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Antineoplastic Agents, Phytogenic - Administration & Dosage
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Chemistry, Multidisciplinary
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Polymer-drug conjugate therapeutics: advances, insights and prospects

Local Cancer Recurrence: The Realities, Challenges, and Opportunities for New Therapies

Biologically Responsive Polymeric Nanoparticles for Drug Delivery

Microscopy and tunable resistive pulse sensing characterization of the swelling of pH-responsive, polymeric expansile nanoparticles

Local drug delivery strategies for cancer treatment: Gels, nanoparticles, polymeric films, rods, and wafers

Prevention of nodal metastases in breast cancer following the lymphatic migration of paclitaxel-loaded expansile nanoparticles

Boolean logic in synthetic biology and biomaterials: Towards living materials in mammalian cell therapeutics

The performance of expansile nanoparticles in a murine model of peritoneal carcinomatosis

Nanoparticle Migration and Delivery of Paclitaxel to Regional Lymph Nodes in a Large Animal Model

Paclitaxel-Loaded Expansile Nanoparticles Delay Local Recurrence in a Heterotopic Murine Non-Small Cell Lung Cancer Model

Ultra-high drug loading improves nanoparticle efficacy against peritoneal mesothelioma

Immunotherapies for locally aggressive cancers

Radiolabeled Biodistribution of Expansile Nanoparticles: Intraperitoneal Administration Results in Tumor Specific Accumulation

Highly Specific and Sensitive Fluorescent Nanoprobes for Image-Guided Resection of Sub-Millimeter Peritoneal Tumors

Pilot-scale production of expansile nanoparticles: Practical methods for clinical scale-up

Tumor Targeted Nanoparticles: A Modern Day Trojan Horse

Nanotechnology applications in thoracic surgery

Ease of Synthesis, Controllable Sizes, and In Vivo Large-Animal-Lymph Migration of Polymeric Nanoparticles

In Vitro Activity of Paclitaxel-Loaded Polymeric Expansile Nanoparticles in Breast Cancer Cells

Synthesis of poly(1,2-glycerol carbonate)-paclitaxel conjugates and their utility as a single high-dose replacement for multi-dose treatment regimens in peritoneal cancer

Nanoparticle drug‐delivery systems for peritoneal cancers: a case study of the design, characterization and development of the expansile nanoparticle

Reinforcement of polymeric nanoassemblies for ultra-high drug loadings, modulation of stiffness and release kinetics, and sustained therapeutic efficacy

Two-Step Delivery: Exploiting the Partition Coefficient Concept to Increase Intratumoral Paclitaxel Concentrations In vivo Using Responsive Nanoparticles

Evaluation of expansile nanoparticle tumor localization and efficacy in a cancer stem cell-derived model of pancreatic peritoneal carcinomatosis

Paclitaxel-Eluting Polymer Film Reduces Locoregional Recurrence and Improves Survival in a Recurrent Sarcoma Model: A Novel Investigational Therapy

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