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Recombinant PaurTx-3, a spider toxin, inhibits sodium channels and decreases membrane excitability in DRG neurons

Biochemical and biophysical research communications, 2020-12, Vol.533 (4), p.958-964

2020

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To4, the first Tityus obscurus β-toxin fully electrophysiologically characterized on human sodium channel isoforms

Peptides (New York, N.Y. : 1980), 2017-09, Vol.95, p.106-115

2017

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Dynamical characterization of inactivation path in voltage-gated Na+ ion channel by non-equilibrium response spectroscopy

Channels (Austin, Tex.), 2016-11, Vol.10 (6), p.478-497

2016

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Ion channel pharmacology under flow: automation via well-plate microfluidics

Assay and drug development technologies, 2012-08, Vol.10 (4), p.313

2012

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Preclinical evaluation of 1,2,4-triazole-based compounds targeting voltage-gated sodium channels (VGSCs) as promising anticonvulsant drug candidates

Bioorganic chemistry, 2020-01, Vol.94, p.103355, Article 103355

2020

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Scorpion beta-toxins and voltage-gated sodium channels: interactions and effects

Frontiers in bioscience (Landmark. Print), 2013-01, Vol.18 (2), p.572

2013

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Three sodium channel mutations from Aedes albopictus confer resistance to Type I, but not Type II pyrethroids

Insect biochemistry and molecular biology, 2020-08, Vol.123, p.103411, Article 103411

2020

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Effect of puerarin on action potential and sodium channel activation in human hypertrophic cardiomyocytes

Bioscience reports, 2020-02, Vol.40 (2)

2020

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Distinct Disulfide Isomers of μ‑Conotoxins KIIIA and KIIIB Block Voltage-Gated Sodium Channels

Biochemistry (Easton), 2012-12, Vol.51 (49), p.9826-9835

2012

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Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain

The Journal of biological chemistry, 2016-07, Vol.291 (27), p.13974-13986

2016

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Naja atra venom peptide reduces pain by selectively blocking the voltage-gated sodium channel Nav1.8

The Journal of biological chemistry, 2019-05, Vol.294 (18), p.7324-7334

2019

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Differential effects of the recombinant toxin PnTx4(5-5) from the spider Phoneutria nigriventer on mammalian and insect sodium channels

Biochimie, 2016-02, Vol.121, p.326-335

2016

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Evolutionary Diversification of Mesobuthus α-Scorpion Toxins Affecting Sodium Channels

Molecular & cellular proteomics, 2012-01, Vol.11 (1), p.M111.012054-M111.012054, Article M111.012054

2012

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Molecular mechanisms of neurotoxin action on voltage-gated sodium channels

Biochimie, 2000-09, Vol.82 (9), p.883-892

2000

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AMPK agonists ameliorate sodium and fluid transport and inflammation in cystic fibrosis airway epithelial cells

American journal of respiratory cell and molecular biology, 2010-06, Vol.42 (6), p.676-684

2010

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Exploring volatile general anesthetic binding to a closed membrane-bound bacterial voltage-gated sodium channel via computation

PLoS computational biology, 2013-06, Vol.9 (6), p.e1003090-e1003090

2013

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Pharmacologically Targeting the Fibroblast Growth Factor 14 Interaction Site on the Voltage-Gated Na + Channel 1.6 Enables Isoform-Selective Modulation

International journal of molecular sciences, 2021-12, Vol.22 (24), p.13541

2021

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Toxin-Resistant Sodium Channels: Parallel Adaptive Evolution across a Complete Gene Family

Molecular biology and evolution, 2008-06, Vol.25 (6), p.1016-1024

2008

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Inhibitory Effectiveness of Gomisin A, a Dibenzocyclooctadiene Lignan Isolated from Schizandra chinensis , on the Amplitude and Gating of Voltage-Gated Na + Current

International journal of molecular sciences, 2020-11, Vol.21 (22), p.8816

2020

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Evans Blue is not a suitable inhibitor of the epithelial sodium channel δ-subunit

Biochemical and biophysical research communications, 2015-10, Vol.466 (3), p.468-474

2015

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Natural meroterpenoids isolated from the plant pathogenic fungus Verticillium albo-atrum with noteworthy modification action against voltage-gated sodium channels of central neurons of Helicoverpa armigera

Pesticide biochemistry and physiology, 2018-01, Vol.144 (C), p.91-99

2018

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Nitric oxide inhibits highly selective sodium channels and the Na+/K+-ATPase in H441 cells

American journal of respiratory cell and molecular biology, 2011-01, Vol.44 (1), p.53-65

2011

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Mechanism of tetrodotoxin block and resistance in sodium channels

Biochemical and biophysical research communications, 2014-03, Vol.446 (1), p.370-374

2014

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Common Molecular Determinants of Tarantula Huwentoxin-IV Inhibition of Na+ Channel Voltage Sensors in Domains II and IV

The Journal of biological chemistry, 2011-08, Vol.286 (31), p.27301-27310

2011

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Gadolinium released by the linear gadolinium-based contrast-agent Gd-DTPA decreases the activity of human epithelial Na+ channels (ENaCs)

Biochimica et biophysica acta. Biomembranes, 2017-05, Vol.1859 (5), p.1040-1048

2017

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Recombinant PaurTx-3, a spider toxin, inhibits sodium channels and decreases membrane excitability in DRG neurons

To4, the first Tityus obscurus β-toxin fully electrophysiologically characterized on human sodium channel isoforms

Dynamical characterization of inactivation path in voltage-gated Na+ ion channel by non-equilibrium response spectroscopy

Ion channel pharmacology under flow: automation via well-plate microfluidics

Preclinical evaluation of 1,2,4-triazole-based compounds targeting voltage-gated sodium channels (VGSCs) as promising anticonvulsant drug candidates

Scorpion beta-toxins and voltage-gated sodium channels: interactions and effects

Three sodium channel mutations from Aedes albopictus confer resistance to Type I, but not Type II pyrethroids

Effect of puerarin on action potential and sodium channel activation in human hypertrophic cardiomyocytes

Distinct Disulfide Isomers of μ‑Conotoxins KIIIA and KIIIB Block Voltage-Gated Sodium Channels

Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain

Naja atra venom peptide reduces pain by selectively blocking the voltage-gated sodium channel Nav1.8

Differential effects of the recombinant toxin PnTx4(5-5) from the spider Phoneutria nigriventer on mammalian and insect sodium channels

Evolutionary Diversification of Mesobuthus α-Scorpion Toxins Affecting Sodium Channels

Molecular mechanisms of neurotoxin action on voltage-gated sodium channels

AMPK agonists ameliorate sodium and fluid transport and inflammation in cystic fibrosis airway epithelial cells

Exploring volatile general anesthetic binding to a closed membrane-bound bacterial voltage-gated sodium channel via computation

Pharmacologically Targeting the Fibroblast Growth Factor 14 Interaction Site on the Voltage-Gated Na + Channel 1.6 Enables Isoform-Selective Modulation

Toxin-Resistant Sodium Channels: Parallel Adaptive Evolution across a Complete Gene Family

Inhibitory Effectiveness of Gomisin A, a Dibenzocyclooctadiene Lignan Isolated from Schizandra chinensis , on the Amplitude and Gating of Voltage-Gated Na + Current

Evans Blue is not a suitable inhibitor of the epithelial sodium channel δ-subunit

Natural meroterpenoids isolated from the plant pathogenic fungus Verticillium albo-atrum with noteworthy modification action against voltage-gated sodium channels of central neurons of Helicoverpa armigera

Nitric oxide inhibits highly selective sodium channels and the Na+/K+-ATPase in H441 cells

Mechanism of tetrodotoxin block and resistance in sodium channels

Common Molecular Determinants of Tarantula Huwentoxin-IV Inhibition of Na+ Channel Voltage Sensors in Domains II and IV

Gadolinium released by the linear gadolinium-based contrast-agent Gd-DTPA decreases the activity of human epithelial Na+ channels (ENaCs)

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