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The mechanism of action of N-acetylcysteine (NAC): The emerging role of H2S and sulfane sulfur species

Pharmacology & therapeutics (Oxford), 2021-12, Vol.228, p.107916-107916, Article 107916

2021

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Meta-analysis of randomised controlled trials with N-acetylcysteine in the treatment of schizophrenia

Australian and New Zealand journal of psychiatry, 2020-05, Vol.54 (5), p.453-466

2020

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Repeated‐Dose Oral N‐Acetylcysteine in Parkinson's Disease: Pharmacokinetics and Effect on Brain Glutathione and Oxidative Stress

Journal of clinical pharmacology, 2018-02, Vol.58 (2), p.158-167

2018

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N-Acetylcysteine as a treatment for sulphur mustard poisoning

Free radical biology & medicine, 2020-12, Vol.161, p.305-320

Sawyer, Thomas W.

2020

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Existing and potential therapeutic uses for N-acetylcysteine: The need for conversion to intracellular glutathione for antioxidant benefits

Pharmacology & therapeutics (Oxford), 2014-02, Vol.141 (2), p.150-159

2014

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Commonality of Ethanol and Nicotine Reinforcement and Relapse in Wistar‐Derived UChB Rats: Inhibition by N‐Acetylcysteine

Alcoholism, clinical and experimental research, 2018-10, Vol.42 (10), p.1988-1999

2018

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The effect of N-acetylcysteine (NAC) on human cognition – A systematic review

Neuroscience and biobehavioral reviews, 2017-07, Vol.78, p.44-56

2017

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Treatment of dilated cardiomyopathy in a mouse model of Friedreich’s ataxia using N-acetylcysteine and identification of alterations in microRNA expression that could be involved in its pathogenesis

Pharmacological research, 2020-09, Vol.159, p.104994-104994, Article 104994

2020

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N‐acetyl cysteine co‐treatment abates perfluorooctanoic acid‐induced reproductive toxicity in male rats

Andrologia, 2021-06, Vol.53 (5), p.e14037-n/a

2021

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The ameliorative effect of N‐acetylcysteine against penconazole induced neurodegenerative and neuroinflammatory disorders in rats

Journal of biochemical and molecular toxicology, 2021-10, Vol.35 (10), p.e22884-n/a

2021

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Effectiveness of N-acetylcysteine in autism spectrum disorders: A meta-analysis of randomized controlled trials

Australian and New Zealand journal of psychiatry, 2021-02, Vol.55 (2), p.196-206

2021

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Protection of human retinal pigment epithelial cells from oxidative damage using cysteine prodrugs

Free radical biology & medicine, 2020-05, Vol.152, p.386-394

2020

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N-Acetylcysteine and Hydrogen Sulfide in Coronavirus Disease 2019

Antioxidants & redox signaling, 2021-11, Vol.35 (14), p.1207-1225

2021

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Glutathione redox imbalance in brain disorders

Current opinion in clinical nutrition and metabolic care, 2015-01, Vol.18 (1), p.89-95

2015

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Therapeutic blockade of inflammation in severe COVID-19 infection with intravenous N-acetylcysteine

Clinical immunology (Orlando, Fla.), 2020-10, Vol.219, p.108544-108544, Article 108544

2020

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Thiol‐water proton exchange of glutathione, cysteine, and N‐acetylcysteine: Implications for CEST MRI

NMR in biomedicine, 2020-01, Vol.33 (1), p.e4188-n/a

2020

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Current etiological comprehension and therapeutic targets of acetaminophen-induced hepatotoxicity

Pharmacological research, 2020-11, Vol.161, p.105102, Article 105102

2020

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Quantitative proteomics using SILAC‐MS identifies N‐acetylcysteine‐solution‐triggered reversal response of renal cell carcinoma cell lines

Journal of cellular biochemistry, 2019-06, Vol.120 (6), p.9506-9513

2019

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N‐acetylcysteine attenuates the cuprizone‐induced behavioral changes and oligodendrocyte loss in male C57BL/7 mice via its anti‐inflammation actions

Journal of neuroscience research, 2018-05, Vol.96 (5), p.803-816

2018

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Improvement of therapeutic potential N-acetylcysteine in acetaminophen hepatotoxicity by encapsulation in PEGylated nano-niosomes

Life sciences (1973), 2020-08, Vol.255, p.117832-117832, Article 117832

2020

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N‐acetylcysteine and prednisolone treatment improved serum biochemistries in suspected flupirtine cases of severe idiosyncratic liver injury

Liver international, 2018-02, Vol.38 (2), p.365-376

2018

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Evaluation of N-acetylcysteine and glutathione as quenching agents for the analysis of halogenated disinfection by-products

Journal of environmental sciences (China), 2022-07, Vol.117, p.71-79

2022

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Intravenous Administration of Stable-Labeled N-Acetylcysteine Demonstrates an Indirect Mechanism for Boosting Glutathione and Improving Redox Status

Journal of pharmaceutical sciences, 2015-08, Vol.104 (8), p.2619-2626

2015

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The efficacy of adjunctive N-acetylcysteine in acute bipolar depression: A randomized placebo-controlled study

Journal of affective disorders, 2019-02, Vol.245, p.1043-1051

2019

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Investigation of the mechanisms behind ochratoxin A‐induced cytotoxicity in human astrocytes and the protective effects of N‐acetylcysteine

Journal of applied toxicology, 2024-09, Vol.44 (9), p.1454-1465

2024

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The mechanism of action of N-acetylcysteine (NAC): The emerging role of H2S and sulfane sulfur species

Meta-analysis of randomised controlled trials with N-acetylcysteine in the treatment of schizophrenia

Repeated‐Dose Oral N‐Acetylcysteine in Parkinson's Disease: Pharmacokinetics and Effect on Brain Glutathione and Oxidative Stress

N-Acetylcysteine as a treatment for sulphur mustard poisoning

Existing and potential therapeutic uses for N-acetylcysteine: The need for conversion to intracellular glutathione for antioxidant benefits

Commonality of Ethanol and Nicotine Reinforcement and Relapse in Wistar‐Derived UChB Rats: Inhibition by N‐Acetylcysteine

The effect of N-acetylcysteine (NAC) on human cognition – A systematic review

Treatment of dilated cardiomyopathy in a mouse model of Friedreich’s ataxia using N-acetylcysteine and identification of alterations in microRNA expression that could be involved in its pathogenesis

N‐acetyl cysteine co‐treatment abates perfluorooctanoic acid‐induced reproductive toxicity in male rats

The ameliorative effect of N‐acetylcysteine against penconazole induced neurodegenerative and neuroinflammatory disorders in rats

Effectiveness of N-acetylcysteine in autism spectrum disorders: A meta-analysis of randomized controlled trials

Protection of human retinal pigment epithelial cells from oxidative damage using cysteine prodrugs

N-Acetylcysteine and Hydrogen Sulfide in Coronavirus Disease 2019

Glutathione redox imbalance in brain disorders

Therapeutic blockade of inflammation in severe COVID-19 infection with intravenous N-acetylcysteine

Thiol‐water proton exchange of glutathione, cysteine, and N‐acetylcysteine: Implications for CEST MRI

Current etiological comprehension and therapeutic targets of acetaminophen-induced hepatotoxicity

Quantitative proteomics using SILAC‐MS identifies N‐acetylcysteine‐solution‐triggered reversal response of renal cell carcinoma cell lines

N‐acetylcysteine attenuates the cuprizone‐induced behavioral changes and oligodendrocyte loss in male C57BL/7 mice via its anti‐inflammation actions

Improvement of therapeutic potential N-acetylcysteine in acetaminophen hepatotoxicity by encapsulation in PEGylated nano-niosomes

N‐acetylcysteine and prednisolone treatment improved serum biochemistries in suspected flupirtine cases of severe idiosyncratic liver injury

Evaluation of N-acetylcysteine and glutathione as quenching agents for the analysis of halogenated disinfection by-products

Intravenous Administration of Stable-Labeled N-Acetylcysteine Demonstrates an Indirect Mechanism for Boosting Glutathione and Improving Redox Status

The efficacy of adjunctive N-acetylcysteine in acute bipolar depression: A randomized placebo-controlled study

Investigation of the mechanisms behind ochratoxin A‐induced cytotoxicity in human astrocytes and the protective effects of N‐acetylcysteine

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