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Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer

Cancer letters, 2015-04, Vol.359 (1), p.47-56

2015

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The PI3K AKT Pathway as a Target for Cancer Treatment

Annual review of medicine, 2016-01, Vol.67 (1), p.11-28

2016

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Management of adverse events associated with idelalisib treatment: expert panel opinion

Leukemia & lymphoma, 2015-10, Vol.56 (10), p.2779-2786

2015

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Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway

Pharmacology & therapeutics (Oxford), 2014-05, Vol.142 (2), p.164-175

2014

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PI3K/Akt signaling in osteosarcoma

Clinica chimica acta, 2015-04, Vol.444, p.182-192

2015

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Targeting the PI3K/AKT/mTOR pathway in triple-negative breast cancer: a review

Breast cancer research and treatment, 2018-06, Vol.169 (3), p.397-406

2018

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The Potential Value of the PI3K/Akt/mTOR Signaling Pathway for Assessing Prognosis in Cervical Cancer and as a Target for Therapy

Journal of cellular biochemistry, 2017-12, Vol.118 (12), p.4163-4169

2017

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Phosphatidylinositol 3‑Kinase (PI3K) and Phosphatidylinositol 3‑Kinase-Related Kinase (PIKK) Inhibitors: Importance of the Morpholine Ring

Journal of medicinal chemistry, 2015-01, Vol.58 (1), p.41-71

2015

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Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer

Biochemical pharmacology, 2014-08, Vol.90 (3), p.197-207

2014

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Effects of d‑Pinitol on Insulin Resistance through the PI3K/Akt Signaling Pathway in Type 2 Diabetes Mellitus Rats

Journal of agricultural and food chemistry, 2015-07, Vol.63 (26), p.6019-6026

2015

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Astaxanthin targets PI3K/Akt signaling pathway toward potential therapeutic applications

Food and chemical toxicology, 2020-11, Vol.145, p.111714-111714, Article 111714

2020

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Targeting PI3 kinase in cancer

Pharmacology & therapeutics (Oxford), 2015-02, Vol.146, p.53-60

2015

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The protective effect of dexmedetomidine on LPS-induced acute lung injury through the HMGB1-mediated TLR4/NF-κB and PI3K/Akt/mTOR pathways

Molecular immunology, 2018-02, Vol.94, p.7-17

2018

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Targeting the PI3K/AKT/mTOR pathway in estrogen receptor-positive breast cancer

Cancer treatment reviews, 2014-08, Vol.40 (7), p.862-871

Ciruelos Gil, Eva Maria

2014

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Maximising the potential of AKT inhibitors as anti-cancer treatments

Pharmacology & therapeutics (Oxford), 2017-04, Vol.172, p.101-115

2017

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Rehmannioside A improves cognitive impairment and alleviates ferroptosis via activating PI3K/AKT/Nrf2 and SLC7A11/GPX4 signaling pathway after ischemia

Journal of ethnopharmacology, 2022-05, Vol.289, p.115021, Article 115021

2022

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Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways

The Journal of nutritional biochemistry, 2017-03, Vol.41, p.124-136

2017

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Gymnemic Acid Ameliorates Hyperglycemia through PI3K/AKT- and AMPK-Mediated Signaling Pathways in Type 2 Diabetes Mellitus Rats

Journal of agricultural and food chemistry, 2019-11, Vol.67 (47), p.13051-13060

2019

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PI3-kinase/Akt/mTOR signaling: Impaired on/off switches in aging, cognitive decline and Alzheimer's disease

Experimental gerontology, 2013-07, Vol.48 (7), p.647-653

Neill, Cora

2013

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Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways

Phytomedicine (Stuttgart), 2017-02, Vol.25, p.93-99

2017

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Chrysin induces death of prostate cancer cells by inducing ROS and ER stress

Journal of cellular physiology, 2017-12, Vol.232 (12), p.3786-3797

2017

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Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway

Cancer letters, 2014-02, Vol.343 (2), p.179-189

2014

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C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits

Gastroenterology (New York, N.Y. 1943), 2016-05, Vol.150 (5), p.1183-1195.e16

2016

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Anticancer mechanisms and clinical application of alkylphospholipids

Biochimica et biophysica acta, 2013-03, Vol.1831 (3), p.663-674

2013

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Sodium Propionate Attenuates the Lipopolysaccharide-Induced Epithelial-Mesenchymal Transition via the PI3K/Akt/mTOR Signaling Pathway

Journal of agricultural and food chemistry, 2020-06, Vol.68 (24), p.6554-6563

2020

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Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer

The PI3K AKT Pathway as a Target for Cancer Treatment

Management of adverse events associated with idelalisib treatment: expert panel opinion

Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway

PI3K/Akt signaling in osteosarcoma

Targeting the PI3K/AKT/mTOR pathway in triple-negative breast cancer: a review

The Potential Value of the PI3K/Akt/mTOR Signaling Pathway for Assessing Prognosis in Cervical Cancer and as a Target for Therapy

Phosphatidylinositol 3‑Kinase (PI3K) and Phosphatidylinositol 3‑Kinase-Related Kinase (PIKK) Inhibitors: Importance of the Morpholine Ring

Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer

Effects of d‑Pinitol on Insulin Resistance through the PI3K/Akt Signaling Pathway in Type 2 Diabetes Mellitus Rats

Astaxanthin targets PI3K/Akt signaling pathway toward potential therapeutic applications

Targeting PI3 kinase in cancer

The protective effect of dexmedetomidine on LPS-induced acute lung injury through the HMGB1-mediated TLR4/NF-κB and PI3K/Akt/mTOR pathways

Targeting the PI3K/AKT/mTOR pathway in estrogen receptor-positive breast cancer

Maximising the potential of AKT inhibitors as anti-cancer treatments

Rehmannioside A improves cognitive impairment and alleviates ferroptosis via activating PI3K/AKT/Nrf2 and SLC7A11/GPX4 signaling pathway after ischemia

Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways

Gymnemic Acid Ameliorates Hyperglycemia through PI3K/AKT- and AMPK-Mediated Signaling Pathways in Type 2 Diabetes Mellitus Rats

PI3-kinase/Akt/mTOR signaling: Impaired on/off switches in aging, cognitive decline and Alzheimer's disease

Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways

Chrysin induces death of prostate cancer cells by inducing ROS and ER stress

Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway

C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits

Anticancer mechanisms and clinical application of alkylphospholipids

Sodium Propionate Attenuates the Lipopolysaccharide-Induced Epithelial-Mesenchymal Transition via the PI3K/Akt/mTOR Signaling Pathway

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