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Bnip3 in mitophagy: Novel insights and potential therapeutic target for diseases of secondary mitochondrial dysfunction

Clinica chimica acta, 2020-07, Vol.506, p.72-83

2020

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CD30 protects EBV-positive diffuse large B-cell lymphoma cells against mitochondrial dysfunction through BNIP3-mediated mitophagy

Cancer letters, 2024-02, Vol.583, p.216616-216616, Article 216616

2024

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Nix/BNIP3L‐dependent mitophagy accounts for airway epithelial cell injury induced by cigarette smoke

Journal of cellular physiology, 2019-08, Vol.234 (8), p.14210-14220

2019

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Methionine deficiency promoted mitophagy via lncRNA PVT1-mediated promoter demethylation of BNIP3 in gastric cancer

The international journal of biochemistry & cell biology, 2021-12, Vol.141, p.106100, Article 106100

2021

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BNIP3 and DAPK1 methylation in peripheral blood leucocytes are noninvasive biomarkers for gastric cancer

Gene, 2024-03, Vol.898, p.148109-148109, Article 148109

2024

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Circ-BNIP3L knockdown alleviates LPS-induced renal tubular epithelial cell injury during sepsis-associated acute kidney injury by miR-370-3p/MYD88 axis

Journal of bioenergetics and biomembranes, 2021-12, Vol.53 (6), p.665-677

2021

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FBXL4 mutation-caused mitochondrial DNA depletion syndrome is driven by BNIP3/BNIP3L-dependent excessive mitophagy

Trends in molecular medicine, 2024-02, Vol.30 (2), p.113-116

2024

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RNF31 alleviates liver steatosis by promoting p53/BNIP3-related mitophagy in hepatocytes

Free radical biology & medicine, 2024-07, Vol.219, p.163-179

2024

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Combining biomarkers of BNIP3 L, S100B, NSE, and accessible measures to predict sepsis-associated encephalopathy: a prospective observational study

Current medical research and opinion, 2024-04, Vol.40 (4), p.575-582

2024

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Pramipexole attenuates neuronal injury in Parkinson's disease by targeting miR-96 to activate BNIP3-mediated mitophagy

Neurochemistry international, 2021-06, Vol.146, p.104972-104972, Article 104972

2021

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Antigen processing and presentation‐related signature‐derived BNIP3 is a novel oncogene and immunotherapy determinant in osteosarcoma based on machine learning and in vitro validation

The journal of gene medicine, 2024-01, Vol.26 (1), p.e3586-n/a

2024

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A homozygous hypomorphic BNIP1 variant causes an increase in autophagosomes and reduced autophagic flux and results in a spondylo‐epiphyseal dysplasia

Human mutation, 2022-05, Vol.43 (5), p.625-642

2022

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Autophagy induced by hypoxia in pulpitis is mediated by HIF-1α/BNIP3

Archives of oral biology, 2024-03, Vol.159, p.105881-105881, Article 105881

2024

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Humanin inhibits lymphatic endothelial cells dysfunction to alleviate myocardial infarction-reperfusion injury via BNIP3-mediated mitophagy

Free radical research, 2024-03, Vol.58 (3), p.180-193

2024

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BNIP3 contributes to silibinin-induced DNA double strand breaks in glioma cells via inhibition of mTOR

Biochemical and biophysical research communications, 2022-01, Vol.589, p.1-8

2022

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Development of Glucose Regulated Protein 94-Selective Inhibitors Based on the BnIm and Radamide Scaffold

Journal of medicinal chemistry, 2016-04, Vol.59 (7), p.3471-3488

2016

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Fulvestrant alleviates cisplatin-induced acute kidney injury via repression of BNIP3-mediated apoptosis and autophagy

Journal of pharmacy and pharmacology, 2024-05, Vol.76 (5), p.489-498

2024

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Mst1 regulates colorectal cancer stress response via inhibiting Bnip3-related mitophagy by activation of JNK/p53 pathway

Cell biology and toxicology, 2018-08, Vol.34 (4), p.263-277

2018

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The HIF-1/ BNIP3 pathway mediates mitophagy to inhibit the pyroptosis of fibroblast-like synoviocytes in rheumatoid arthritis

International immunopharmacology, 2024-01, Vol.127, p.111378-111378, Article 111378

2024

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Induction of autophagy biomarker BNIP3 requires a JAK2/STAT3 and MT1-MMP signaling interplay in Concanavalin-A-activated U87 glioblastoma cells

Cellular signalling, 2014-05, Vol.26 (5), p.917-924

2014

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Arsenite-induced cytotoxicity is regulated by p38-SQSTM1/p62 and JNK-BNIP3L/Nix signaling in lung cancer cells

Biochemical and biophysical research communications, 2022-01, Vol.587, p.16-23

2022

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Yessotoxin induces ER-stress followed by autophagic cell death in glioma cells mediated by mTOR and BNIP3

Cellular signalling, 2014-02, Vol.26 (2), p.419-432

2014

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BNIP3 contributes to the glutamine-driven aggressive behavior of melanoma cells

Biological chemistry, 2019-02, Vol.400 (2), p.187-193

2019

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miR-26 inhibits proliferation and promotes apoptosis of multiple myeloma cells by targeting BNIP3

Cellular and Molecular Biology, 2023-11, Vol.69 (11), p.260-265

2023

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Frequent promoter hypermethylation and down regulation of BNIP3: An early event during gallbladder cancer progression

Digestive and liver disease, 2022-09, Vol.54 (9), p.1257-1263

2022

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Bnip3 in mitophagy: Novel insights and potential therapeutic target for diseases of secondary mitochondrial dysfunction

CD30 protects EBV-positive diffuse large B-cell lymphoma cells against mitochondrial dysfunction through BNIP3-mediated mitophagy

Nix/BNIP3L‐dependent mitophagy accounts for airway epithelial cell injury induced by cigarette smoke

Methionine deficiency promoted mitophagy via lncRNA PVT1-mediated promoter demethylation of BNIP3 in gastric cancer

BNIP3 and DAPK1 methylation in peripheral blood leucocytes are noninvasive biomarkers for gastric cancer

Circ-BNIP3L knockdown alleviates LPS-induced renal tubular epithelial cell injury during sepsis-associated acute kidney injury by miR-370-3p/MYD88 axis

FBXL4 mutation-caused mitochondrial DNA depletion syndrome is driven by BNIP3/BNIP3L-dependent excessive mitophagy

RNF31 alleviates liver steatosis by promoting p53/BNIP3-related mitophagy in hepatocytes

Combining biomarkers of BNIP3 L, S100B, NSE, and accessible measures to predict sepsis-associated encephalopathy: a prospective observational study

Pramipexole attenuates neuronal injury in Parkinson's disease by targeting miR-96 to activate BNIP3-mediated mitophagy

Antigen processing and presentation‐related signature‐derived BNIP3 is a novel oncogene and immunotherapy determinant in osteosarcoma based on machine learning and in vitro validation

A homozygous hypomorphic BNIP1 variant causes an increase in autophagosomes and reduced autophagic flux and results in a spondylo‐epiphyseal dysplasia

Autophagy induced by hypoxia in pulpitis is mediated by HIF-1α/BNIP3

Humanin inhibits lymphatic endothelial cells dysfunction to alleviate myocardial infarction-reperfusion injury via BNIP3-mediated mitophagy

BNIP3 contributes to silibinin-induced DNA double strand breaks in glioma cells via inhibition of mTOR

Development of Glucose Regulated Protein 94-Selective Inhibitors Based on the BnIm and Radamide Scaffold

Fulvestrant alleviates cisplatin-induced acute kidney injury via repression of BNIP3-mediated apoptosis and autophagy

Mst1 regulates colorectal cancer stress response via inhibiting Bnip3-related mitophagy by activation of JNK/p53 pathway

The HIF-1/ BNIP3 pathway mediates mitophagy to inhibit the pyroptosis of fibroblast-like synoviocytes in rheumatoid arthritis

Induction of autophagy biomarker BNIP3 requires a JAK2/STAT3 and MT1-MMP signaling interplay in Concanavalin-A-activated U87 glioblastoma cells

Arsenite-induced cytotoxicity is regulated by p38-SQSTM1/p62 and JNK-BNIP3L/Nix signaling in lung cancer cells

Yessotoxin induces ER-stress followed by autophagic cell death in glioma cells mediated by mTOR and BNIP3

BNIP3 contributes to the glutamine-driven aggressive behavior of melanoma cells

miR-26 inhibits proliferation and promotes apoptosis of multiple myeloma cells by targeting BNIP3

Frequent promoter hypermethylation and down regulation of BNIP3: An early event during gallbladder cancer progression

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