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Endothelial NADPH oxidases: which NOX to target in vascular disease?

Trends in endocrinology and metabolism, 2014-09, Vol.25 (9), p.452-463

2014

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Molecular mechanisms of hypertension: role of Nox family NADPH oxidases

Current opinion in nephrology and hypertension, 2009-03, Vol.18 (2), p.122-127

2009

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Cinnamaldehyde ameliorates LPS-induced cardiac dysfunction via TLR4-NOX4 pathway: The regulation of autophagy and ROS production

Journal of molecular and cellular cardiology, 2016-12, Vol.101, p.11-24

2016

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Increased Expression of DUOX2 Is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine

Gastroenterology (New York, N.Y. 1943), 2015-12, Vol.149 (7), p.1849-1859

2015

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Low-grade endotoxemia, gut permeability and platelet activation in community-acquired pneumonia

The Journal of infection, 2016-08, Vol.73 (2), p.107-114

2016

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Hu antigen R is required for NOX-1 but not NOX-4 regulation by inflammatory stimuli in vascular smooth muscle cells

Journal of hypertension, 2016-02, Vol.34 (2), p.253-265

2016

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Berberine inhibits NADPH oxidase mediated superoxide anion production in macrophages

Canadian journal of physiology and pharmacology, 2010-03, Vol.88 (3), p.369

2010

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Chronic granulomatous disease

Hematology/oncology clinics of North America, 2013-02, Vol.27 (1), p.89

Holland, Steven M

2013

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The NOX1/4 inhibitor GKT136901 as selective and direct scavenger of peroxynitrite

Current medicinal chemistry, 2014-01, Vol.21 (3), p.365

2014

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NOX2, NOX4, and mitochondrial-derived reactive oxygen species contribute to angiopoietin-1 signaling and angiogenic responses in endothelial cells

Vascular pharmacology, 2017-05, Vol.92, p.22-32

2017

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Variants in Nicotinamide Adenine Dinucleotide Phosphate Oxidase Complex Components Determine Susceptibility to Very Early Onset Inflammatory Bowel Disease

Gastroenterology (New York, N.Y. 1943), 2014-09, Vol.147 (3), p.680-689.e2

2014

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MicroRNA-25-dependent up-regulation of NADPH oxidase 4 (NOX4) mediates hypercholesterolemia-induced oxidative/nitrative stress and subsequent dysfunction in the heart

Journal of molecular and cellular cardiology, 2013-09, Vol.62, p.111-121

2013

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Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity

Journal of hepatology, 2008-12, Vol.49 (6), p.965-976

2008

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CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells

Experimental hematology, 2015-10, Vol.43 (10), p.838-848.e3

2015

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Activation of the ACE2/Ang-(1–7)/Mas pathway reduces oxygen–glucose deprivation-induced tissue swelling, ROS production, and cell death in mouse brain with angiotensin II overproduction

Neuroscience, 2014-07, Vol.273, p.39-51

2014

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Targeting NADPH oxidases in vascular pharmacology

Vascular pharmacology, 2012-05, Vol.56 (5), p.216-231

2012

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The Protective Effect of Vitexin Compound B-1 on Rat Cerebral I/R Injury through a Mechanism Involving Modulation of miR-92b/NOX4 Pathway

CNS & neurological disorders drug targets, 2023, Vol.22 (1), p.137

2023

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Galectin-3 mediates the pulmonary arterial hypertension-induced right ventricular remodeling through interacting with NADPH oxidase 4

Journal of the American Society of Hypertension, 2017-05, Vol.11 (5), p.275

2017

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Paeoniflorin protects myocardial cell from doxorubicin-induced apoptosis through inhibition of NADPH oxidase

Canadian journal of physiology and pharmacology, 2012-12, Vol.90 (12), p.1569

2012

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Early lipopolysaccharide-induced reactive oxygen species production evokes necrotic cell death in human umbilical vein endothelial cells

Journal of hypertension, 2009-06, Vol.27 (6), p.1202-1216

2009

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Nitroxidative Signaling Mechanisms in Pathological Pain

Trends in neurosciences (Regular ed.), 2016-12, Vol.39 (12), p.862-879

2016

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Redox signaling, Nox5 and vascular remodeling in hypertension

Current opinion in nephrology and hypertension, 2015-09, Vol.24 (5), p.425-433

2015

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Versatile roles of plant NADPH oxidases and emerging concepts

Biotechnology advances, 2014-05, Vol.32 (3), p.551-563

2014

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Oxidative stress in atrial fibrillation: An emerging role of NADPH oxidase

Journal of molecular and cellular cardiology, 2013-09, Vol.62, p.72-79

2013

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Endothelial NADPH oxidases: which NOX to target in vascular disease?

Molecular mechanisms of hypertension: role of Nox family NADPH oxidases

Cinnamaldehyde ameliorates LPS-induced cardiac dysfunction via TLR4-NOX4 pathway: The regulation of autophagy and ROS production

Increased Expression of DUOX2 Is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine

Low-grade endotoxemia, gut permeability and platelet activation in community-acquired pneumonia

Hu antigen R is required for NOX-1 but not NOX-4 regulation by inflammatory stimuli in vascular smooth muscle cells

Berberine inhibits NADPH oxidase mediated superoxide anion production in macrophages

Chronic granulomatous disease

The NOX1/4 inhibitor GKT136901 as selective and direct scavenger of peroxynitrite

NOX2, NOX4, and mitochondrial-derived reactive oxygen species contribute to angiopoietin-1 signaling and angiogenic responses in endothelial cells

Variants in Nicotinamide Adenine Dinucleotide Phosphate Oxidase Complex Components Determine Susceptibility to Very Early Onset Inflammatory Bowel Disease

MicroRNA-25-dependent up-regulation of NADPH oxidase 4 (NOX4) mediates hypercholesterolemia-induced oxidative/nitrative stress and subsequent dysfunction in the heart

Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity

Protein disulfide isomerase-mediated transcriptional upregulation of Nox1 contributes to vascular dysfunction in hypertension

CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells

Activation of the ACE2/Ang-(1–7)/Mas pathway reduces oxygen–glucose deprivation-induced tissue swelling, ROS production, and cell death in mouse brain with angiotensin II overproduction

Targeting NADPH oxidases in vascular pharmacology

The Protective Effect of Vitexin Compound B-1 on Rat Cerebral I/R Injury through a Mechanism Involving Modulation of miR-92b/NOX4 Pathway

Galectin-3 mediates the pulmonary arterial hypertension-induced right ventricular remodeling through interacting with NADPH oxidase 4

Paeoniflorin protects myocardial cell from doxorubicin-induced apoptosis through inhibition of NADPH oxidase

Early lipopolysaccharide-induced reactive oxygen species production evokes necrotic cell death in human umbilical vein endothelial cells

Nitroxidative Signaling Mechanisms in Pathological Pain

Redox signaling, Nox5 and vascular remodeling in hypertension

Versatile roles of plant NADPH oxidases and emerging concepts

Oxidative stress in atrial fibrillation: An emerging role of NADPH oxidase

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