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LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway

Cellular and molecular life sciences : CMLS, 2013-01, Vol.70 (1), p.121-136

2013

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Helicobacter pylori stimulates host vascular endothelial growth factor‐A (vegf‐A) gene expression via MEK/ERK‐dependent activation of Sp1 and Sp3

The FASEB journal, 2004-01, Vol.18 (1), p.218-220

2004

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Singapore grouper iridovirus, a large DNA virus, induces nonapoptotic cell death by a cell type dependent fashion and evokes ERK signaling

Apoptosis (London), 2011-08, Vol.16 (8), p.831-845

2011

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CSE1L Links cAMP/PKA and Ras/ERK pathways and regulates the expressions and phosphorylations of ERK1/2, CREB, and MITF in melanoma cells

Molecular carcinogenesis, 2016-11, Vol.55 (11), p.1542-1552

2016

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AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer

Cellular and molecular life sciences : CMLS, 2023-01, Vol.80 (1), p.12, Article 12

2023

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The Allosteric Switch and Conformational States in Ras GTPase Affected by Small Molecules

The Enzymes, 2013, Vol.33, p.41-67

2013

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Inhibition of lipid phosphate phosphatase activity by VPC32183 suppresses the ability of diacylglycerol pyrophosphate to activate ERK1/2 MAP kinases

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2012-11, Vol.1821 (11), p.1394-1405

2012

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Mapping of signaling pathways by functional interaction proteomics

Methods in molecular biology (Clifton, N.J.), 2008, Vol.484, p.177

2008

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Anomalous signal from S atoms in protein crystallographic data from an X-ray free-electron laser

Acta crystallographica. Section D, Biological crystallography., 2013-05, Vol.69 (5), p.838-842

2013

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Metabolic regulation of RA macrophages is distinct from RA fibroblasts and blockade of glycolysis alleviates inflammatory phenotype in both cell types

Cellular and molecular life sciences : CMLS, 2021-12, Vol.78 (23), p.7693-7707

2021

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CDK5 downregulation enhances synaptic plasticity

Cellular and molecular life sciences : CMLS, 2017-01, Vol.74 (1), p.153-172

2017

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Circulating cord blood HDL-S1P complex preserves the integrity of the feto-placental vasculature

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2020-04, Vol.1865 (4), p.158632-158632, Article 158632

2020

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MIF interacts with CXCR7 to promote receptor internalization, ERK1/2 and ZAP‐70 signaling, and lymphocyte chemotaxis

The FASEB journal, 2015-11, Vol.29 (11), p.4497-4511

2015

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SREBP1 regulates mitochondrial metabolism in oncogenic KRAS expressing NSCLC

The FASEB journal, 2020-08, Vol.34 (8), p.10574-10589

2020

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Phosphoproteomics Profiling Defines a Target Landscape of the Basophilic Protein Kinases AKT, S6K, and RSK in Skeletal Myotubes

Journal of proteome research, 2023-03, Vol.22 (3), p.768-789

2023

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Encoding BRAF inhibitor functions in protein degraders

RSC medicinal chemistry, 2022-06, Vol.13 (6), p.731-736

2022

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Fluid shear stress-induced TGF-β/ALK5 signaling in renal epithelial cells is modulated by MEK1/2

Cellular and molecular life sciences : CMLS, 2017-06, Vol.74 (12), p.2283-2298

2017

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Mechanistic principles of RAF kinase signaling

Cellular and molecular life sciences : CMLS, 2011-02, Vol.68 (4), p.553-565

2011

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Multiepitope tissue analysis reveals SPPL3-mediated ADAM10 activation as a key step in the transformation of melanocytes

Science signaling, 2017-03, Vol.10 (470)

2017

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Peroxiredoxins 3 and 4 Are Overexpressed in Prostate Cancer Tissue and Affect the Proliferation of Prostate Cancer Cells in Vitro

Journal of proteome research, 2012-04, Vol.11 (4), p.2452-2466

2012

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S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells

The FASEB journal, 2006-03, Vol.20 (3), p.518-520

2006

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Cellular and subcellular context determine outputs from signaling biosensors

Methods in cell biology, 2016, Vol.132, p.319

2016

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Characterization of a Ras Mutant with Identical GDP- and GTP-Bound Structures

Biochemistry (Easton), 2009-12, Vol.48 (48), p.11449-11457

2009

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Tetrandrine inhibits cell migration and invasion in human nasopharyngeal carcinoma NPC‐TW 039 cells through inhibiting MAPK and RhoA signaling pathways

Journal of food biochemistry, 2020-10, Vol.44 (10), p.e13387-n/a

2020

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LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway

Helicobacter pylori stimulates host vascular endothelial growth factor‐A (vegf‐A) gene expression via MEK/ERK‐dependent activation of Sp1 and Sp3

Singapore grouper iridovirus, a large DNA virus, induces nonapoptotic cell death by a cell type dependent fashion and evokes ERK signaling

CSE1L Links cAMP/PKA and Ras/ERK pathways and regulates the expressions and phosphorylations of ERK1/2, CREB, and MITF in melanoma cells

AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer

The Allosteric Switch and Conformational States in Ras GTPase Affected by Small Molecules

Inhibition of lipid phosphate phosphatase activity by VPC32183 suppresses the ability of diacylglycerol pyrophosphate to activate ERK1/2 MAP kinases

Mapping of signaling pathways by functional interaction proteomics

Anomalous signal from S atoms in protein crystallographic data from an X-ray free-electron laser

Metabolic regulation of RA macrophages is distinct from RA fibroblasts and blockade of glycolysis alleviates inflammatory phenotype in both cell types

CDK5 downregulation enhances synaptic plasticity

Circulating cord blood HDL-S1P complex preserves the integrity of the feto-placental vasculature

MIF interacts with CXCR7 to promote receptor internalization, ERK1/2 and ZAP‐70 signaling, and lymphocyte chemotaxis

SREBP1 regulates mitochondrial metabolism in oncogenic KRAS expressing NSCLC

Phosphoproteomics Profiling Defines a Target Landscape of the Basophilic Protein Kinases AKT, S6K, and RSK in Skeletal Myotubes

Encoding BRAF inhibitor functions in protein degraders

Fluid shear stress-induced TGF-β/ALK5 signaling in renal epithelial cells is modulated by MEK1/2

Mechanistic principles of RAF kinase signaling

Multiepitope tissue analysis reveals SPPL3-mediated ADAM10 activation as a key step in the transformation of melanocytes

Peroxiredoxins 3 and 4 Are Overexpressed in Prostate Cancer Tissue and Affect the Proliferation of Prostate Cancer Cells in Vitro

Vemurafenib potently induces endoplasmic reticulum stress-mediated apoptosis in BRAFV600E melanoma cells

S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells

Cellular and subcellular context determine outputs from signaling biosensors

Characterization of a Ras Mutant with Identical GDP- and GTP-Bound Structures

Tetrandrine inhibits cell migration and invasion in human nasopharyngeal carcinoma NPC‐TW 039 cells through inhibiting MAPK and RhoA signaling pathways

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