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Synthesis and Evaluation of N‑Phenyl-3-sulfamoyl-benzamide Derivatives as Capsid Assembly Modulators Inhibiting Hepatitis B Virus (HBV)

Journal of medicinal chemistry, 2018-07, Vol.61 (14), p.6247-6260

2018

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Antiviral profiling of the capsid assembly modulator BAY41-4109 on full-length HBV genotype A-H clinical isolates and core site-directed mutants in vitro

Antiviral research, 2017-08, Vol.144, p.205-215

2017

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Discovery and Early Development of TMC647055, a Non-Nucleoside Inhibitor of the Hepatitis C Virus NS5B Polymerase

Journal of medicinal chemistry, 2014-03, Vol.57 (5), p.1880-1892

2014

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Structure-Based Macrocyclization Yields Hepatitis C Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties

Angewandte Chemie (International ed.), 2012-05, Vol.51 (19), p.4637-4640

2012

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Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055

Bioorganic & medicinal chemistry letters, 2012-07, Vol.22 (13), p.4437-4443

2012

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Finger-loop inhibitors of the HCV NS5b polymerase. Part 1: Discovery and optimization of novel 1,6- and 2,6-macrocyclic indole series

Bioorganic & medicinal chemistry letters, 2012-07, Vol.22 (13), p.4431-4436

2012

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Structure-Based Macrocyclization Yields HepatitisC Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties

Angewandte Chemie International Edition, 2012-05, Vol.51 (19), p.4637

International ed. in English, 2012

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Identification of HIV-1 reverse transcriptase inhibitors using a scintillation proximity assay

Methods in molecular biology (Clifton, N.J.), 2013, Vol.1030, p.19

2013

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Resistance to antiretroviral therapy among patients in Uganda

Journal of acquired immune deficiency syndromes (1999), 2001-04, Vol.26 (5), p.495

2001

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Genotypic and Phenotypic Evidence of Different Drug-Resistance Mutation Patterns between B and Non-B Subtype Isolates of Human Immunodeficiency Virus Type 1 found in Brazilian Patients Failing HAART

Virus genes, 2001-01, Vol.23 (2), p.193-202

2001

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Structure-Based Macrocyclization Yields Hepatitis C Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties

Angewandte Chemie, 2012-05, Vol.124 (19), p.4715-4718

2012

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Structure-Based Macrocyclization Yields HepatitisC Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties

Angewandte Chemie, 2012-05, Vol.124 (19), p.4715

2012

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Efficacy, tolerance, and pharmacokinetics of the combination of stavudine, nevirapine, nelfinavir, and saquinavir as salvage regimen after ritonavir or indinavir failure

AIDS research and human retroviruses, 2001-01, Vol.17 (2), p.93-98

2001

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Synthesis and Evaluation of N‑Phenyl-3-sulfamoyl-benzamide Derivatives as Capsid Assembly Modulators Inhibiting Hepatitis B Virus (HBV)

Antiviral profiling of the capsid assembly modulator BAY41-4109 on full-length HBV genotype A-H clinical isolates and core site-directed mutants in vitro

Discovery and Early Development of TMC647055, a Non-Nucleoside Inhibitor of the Hepatitis C Virus NS5B Polymerase

Structure-Based Macrocyclization Yields Hepatitis C Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties

Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055

Finger-loop inhibitors of the HCV NS5b polymerase. Part 1: Discovery and optimization of novel 1,6- and 2,6-macrocyclic indole series

Structure-Based Macrocyclization Yields HepatitisC Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties

Identification of HIV-1 reverse transcriptase inhibitors using a scintillation proximity assay

Resistance to antiretroviral therapy among patients in Uganda

Genotypic and Phenotypic Evidence of Different Drug-Resistance Mutation Patterns between B and Non-B Subtype Isolates of Human Immunodeficiency Virus Type 1 found in Brazilian Patients Failing HAART

Structure-Based Macrocyclization Yields Hepatitis C Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties

Structure-Based Macrocyclization Yields HepatitisC Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties

Efficacy, tolerance, and pharmacokinetics of the combination of stavudine, nevirapine, nelfinavir, and saquinavir as salvage regimen after ritonavir or indinavir failure

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