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Software for systems biology: from tools to integrated platforms

Nature reviews. Genetics, 2011-12, Vol.12 (12), p.821-832

2011

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Potential Functional Restoration of Corneal Endothelial Cells in Fuchs Endothelial Corneal Dystrophy by ROCK Inhibitor (Ripasudil)

American journal of ophthalmology, 2021-04, Vol.224, p.185-199

2021

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Gankyrin drives metabolic reprogramming to promote tumorigenesis, metastasis and drug resistance through activating β-catenin/c-Myc signaling in human hepatocellular carcinoma

Cancer letters, 2019-02, Vol.443, p.34-46

2019

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Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies

Genome Biology, 2016-05, Vol.17 (1), p.115-115, Article 115

2016

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Genome-wide identification of transcription factors that are critical to non-small cell lung cancer

Cancer letters, 2018-10, Vol.434, p.132-143

2018

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Small molecule inhibition of polo-like kinase 1 by volasertib (BI 6727) causes significant melanoma growth delay and regression in vivo

Cancer letters, 2017-01, Vol.385, p.179-187

2017

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In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B

Cancer letters, 2016-01, Vol.370 (2), p.185-197

2016

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Cuproptosis identifies respiratory subtype of renal cancer that confers favorable prognosis

Apoptosis (London), 2022-12, Vol.27 (11-12), p.1004-1014

2022

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PI3K blockage synergizes with PLK1 inhibition preventing endoreduplication and enhancing apoptosis in anaplastic thyroid cancer

Cancer letters, 2018-12, Vol.439, p.56-65

2018

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The biological interactions between kynurenine and AhR in melanocytes: in vitro studies

Amino acids, 2023-07, Vol.55 (7), p.947-954

2023

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Targeting c-Myc: JQ1 as a promising option for c-Myc-amplified esophageal squamous cell carcinoma

Cancer letters, 2018-04, Vol.419, p.64-74

2018

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Antiproliferative and proapoptotic activities of 4-hydroxybenzoic acid-based inhibitors of histone deacetylases

Cancer letters, 2014-02, Vol.343 (1), p.134-146

2014

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Chidamide works synergistically with Dasatinib by inducing cell-cycle arrest and apoptosis in acute myeloid leukemia cells

Molecular and cellular biochemistry, 2023-04, Vol.478 (4), p.851-860

2023

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Advanced network pharmacology study reveals multi-pathway and multi-gene regulatory molecular mechanism of Bacopa monnieri in liver cancer based on data mining, molecular modeling, and microarray data analysis

Computers in biology and medicine, 2023-07, Vol.161, p.107059-107059, Article 107059

2023

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The NUPR1/p73 axis contributes to sorafenib resistance in hepatocellular carcinoma

Cancer letters, 2021-10, Vol.519, p.250-262

2021

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Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells

Journal of neuro-oncology, 2023-05, Vol.163 (1), p.143-158

2023

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HDAC11 mediates the ubiquitin-dependent degradation of p53 and inhibits the anti-leukemia effect of PD0166285

Medical oncology (Northwood, London, England), 2023-10, Vol.40 (11), p.325-325, Article 325

2023

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Induction of cell death in pancreatic ductal adenocarcinoma by indirubin 3’-oxime and 5-methoxyindirubin 3’-oxime in vitro and in vivo

Cancer letters, 2017-07, Vol.397, p.72-82

2017

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All-trans retinoic acid exerts selective anti-FLT3-ITD acute myeloid leukemia efficacy through downregulating Chk1 kinase

Cancer letters, 2020-03, Vol.473, p.130-138

2020

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Palbociclib, a selective CDK4/6 inhibitor, enhances the effect of selumetinib in RAS-driven non-small cell lung cancer

Cancer letters, 2017-11, Vol.408, p.130-137

2017

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KCNN4 promotes invasion and metastasis through the MAPK/ERK pathway in hepatocellular carcinoma

Journal of investigative medicine, 2020-01, Vol.68 (1), p.68-74

2020

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Piceatannol, a natural stilbene from grapes, induces G1 cell cycle arrest in androgen-insensitive DU145 human prostate cancer cells via the inhibition of CDK activity

Cancer letters, 2009-11, Vol.285 (2), p.166-173

2009

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Thyroid receptor-interacting protein 13 and EGFR form a feedforward loop promoting glioblastoma growth

Cancer letters, 2020-11, Vol.493, p.156-166

2020

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Clinical Efficacy of Vaccaria segetalis Seeds and Gleditsia sinensis Lam Thorns on Prostate Cancer: A Preliminary Mechanism Analysis based on Network Pharmacology

Letters in drug design & discovery, 2024-08, Vol.21 (10), p.1874-1885

2024

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Software for systems biology: from tools to integrated platforms

Potential Functional Restoration of Corneal Endothelial Cells in Fuchs Endothelial Corneal Dystrophy by ROCK Inhibitor (Ripasudil)

Gankyrin drives metabolic reprogramming to promote tumorigenesis, metastasis and drug resistance through activating β-catenin/c-Myc signaling in human hepatocellular carcinoma

Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies

Genome-wide identification of transcription factors that are critical to non-small cell lung cancer

Small molecule inhibition of polo-like kinase 1 by volasertib (BI 6727) causes significant melanoma growth delay and regression in vivo

In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B

Cuproptosis identifies respiratory subtype of renal cancer that confers favorable prognosis

PI3K blockage synergizes with PLK1 inhibition preventing endoreduplication and enhancing apoptosis in anaplastic thyroid cancer

The biological interactions between kynurenine and AhR in melanocytes: in vitro studies

Targeting c-Myc: JQ1 as a promising option for c-Myc-amplified esophageal squamous cell carcinoma

Antiproliferative and proapoptotic activities of 4-hydroxybenzoic acid-based inhibitors of histone deacetylases

Chidamide works synergistically with Dasatinib by inducing cell-cycle arrest and apoptosis in acute myeloid leukemia cells

Advanced network pharmacology study reveals multi-pathway and multi-gene regulatory molecular mechanism of Bacopa monnieri in liver cancer based on data mining, molecular modeling, and microarray data analysis

The NUPR1/p73 axis contributes to sorafenib resistance in hepatocellular carcinoma

Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells

HDAC11 mediates the ubiquitin-dependent degradation of p53 and inhibits the anti-leukemia effect of PD0166285

Pro-differentiating and radiosensitizing effects of inhibiting HDACs by PXD-101 (Belinostat) in in vitro and in vivo models of human rhabdomyosarcoma cell lines

Induction of cell death in pancreatic ductal adenocarcinoma by indirubin 3’-oxime and 5-methoxyindirubin 3’-oxime in vitro and in vivo

All-trans retinoic acid exerts selective anti-FLT3-ITD acute myeloid leukemia efficacy through downregulating Chk1 kinase

Palbociclib, a selective CDK4/6 inhibitor, enhances the effect of selumetinib in RAS-driven non-small cell lung cancer

KCNN4 promotes invasion and metastasis through the MAPK/ERK pathway in hepatocellular carcinoma

Piceatannol, a natural stilbene from grapes, induces G1 cell cycle arrest in androgen-insensitive DU145 human prostate cancer cells via the inhibition of CDK activity

Thyroid receptor-interacting protein 13 and EGFR form a feedforward loop promoting glioblastoma growth

Clinical Efficacy of Vaccaria segetalis Seeds and Gleditsia sinensis Lam Thorns on Prostate Cancer: A Preliminary Mechanism Analysis based on Network Pharmacology

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