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A Reversible and Selective Inhibitor of Monoacylglycerol Lipase Ameliorates Multiple Sclerosis

Angewandte Chemie (International ed.), 2014-12, Vol.53 (50), p.13765-13770

International ed. in English, 2014

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2‐AG limits Theiler's virus induced acute neuroinflammation by modulating microglia and promoting MDSCs

Glia, 2018-07, Vol.66 (7), p.1447-1463

2018

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Blocking Ras inhibition as an antitumor strategy

Seminars in cancer biology, 2019-02, Vol.54, p.91-100

2019

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The constitutive production of the endocannabinoid 2-arachidonoylglycerol participates in oligodendrocyte differentiation

Glia, 2010-12, Vol.58 (16), p.1913-1927

2010

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Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling

Chemistry : a European journal, 2017-01, Vol.23 (7), p.1676-1685

2017

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Effect of anandamide uptake inhibition in the production of nitric oxide and in the release of cytokines in astrocyte cultures

Glia, 2005-11, Vol.52 (2), p.163-168

2005

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Chemical Probes for the Recognition of Cannabinoid Receptors in Native Systems

Angewandte Chemie (International ed.), 2012-07, Vol.51 (28), p.6896-6899

International ed. in English, 2012

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A new fluorescent probe for the visualization of progerin

Bioorganic chemistry, 2024-01, Vol.142, p.106967-106967, Article 106967

2024

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Mitochondrial CB₁ receptors regulate neuronal energy metabolism

Nature neuroscience, 2012-03, Vol.15 (4), p.558-564

2012

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Chemoproteomic Approach to Explore the Target Profile of GPCR ligands: Application to 5-HT1A and 5-HT6 Receptors

Chemistry : a European journal, 2016-01, Vol.22 (4), p.1313-1321

2016

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Serum endocannabinoid levels in suicide attempters: A pilot study

European neuropsychopharmacology, 2020-11, Vol.40, p.52-60

2020

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The medicinal chemistry of agents targeting monoacylglycerol lipase

Current topics in medicinal chemistry, 2008-02, Vol.8 (3), p.231-246

2008

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Chemistry for the Identification of Therapeutic Targets: Recent Advances and Future Directions

European journal of organic chemistry, 2021-03, Vol.2021 (9), p.1307-1320

2021

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A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia

Journal of medicinal chemistry, 2019-07, Vol.62 (13), p.6035-6046

2019

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Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice

Journal of medicinal chemistry, 2022-08, Vol.65 (16), p.10956-10974

2022

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A Fluorescent Probe to Unravel Functional Features of Cannabinoid Receptor CB1 in Human Blood and Tonsil Immune System Cells

Bioconjugate chemistry, 2018-02, Vol.29 (2), p.382-389

2018

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New Synthetic Inhibitors of Fatty Acid Synthase with Anticancer Activity

Journal of medicinal chemistry, 2012-06, Vol.55 (11), p.5013-5023

2012

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Therapeutic perspectives of inhibitors of endocannabinoid degradation

Current drug targets. CNS & neurological disorders, 2005-12, Vol.4 (6), p.697-707

Ortega-Gutiérrez, Silvia

2005

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CB1 and CB2 cannabinoid receptor binding studies based on modeling and mutagenesis approaches

Mini reviews in medicinal chemistry, 2005-07, Vol.5 (7), p.651-658

2005

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Activation of the endocannabinoid system as therapeutic approach in a murine model of multiple sclerosis

The FASEB journal, 2005-08, Vol.19 (10), p.1338-1340

2005

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New Inhibitors of Angiogenesis with Antitumor Activity in Vivo

Journal of medicinal chemistry, 2015-05, Vol.58 (9), p.3757-3766

2015

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Structure–Activity Relationship of a New Series of Reversible Dual Monoacylglycerol Lipase/Fatty Acid Amide Hydrolase Inhibitors

Journal of medicinal chemistry, 2012-01, Vol.55 (2), p.824-836

2012

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Inside Cover: A Reversible and Selective Inhibitor of Monoacylglycerol Lipase Ameliorates Multiple Sclerosis (Angew. Chem. Int. Ed. 50/2014)

Angewandte Chemie (International ed.), 2014-12, Vol.53 (50), p.13624-13624

International ed. in English, 2014

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Development of Endocannabinoid-Based Chemical Probes for the Study of Cannabinoid Receptors

Journal of medicinal chemistry, 2011-07, Vol.54 (14), p.5265-5269

2011

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A Reversible and Selective Inhibitor of Monoacylglycerol Lipase Ameliorates Multiple Sclerosis

2‐AG limits Theiler's virus induced acute neuroinflammation by modulating microglia and promoting MDSCs

Blocking Ras inhibition as an antitumor strategy

The constitutive production of the endocannabinoid 2-arachidonoylglycerol participates in oligodendrocyte differentiation

Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling

Effect of anandamide uptake inhibition in the production of nitric oxide and in the release of cytokines in astrocyte cultures

Chemical Probes for the Recognition of Cannabinoid Receptors in Native Systems

A new fluorescent probe for the visualization of progerin

Mitochondrial CB₁ receptors regulate neuronal energy metabolism

Chemoproteomic Approach to Explore the Target Profile of GPCR ligands: Application to 5-HT1A and 5-HT6 Receptors

Serum endocannabinoid levels in suicide attempters: A pilot study

The medicinal chemistry of agents targeting monoacylglycerol lipase

Chemistry for the Identification of Therapeutic Targets: Recent Advances and Future Directions

A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration

A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia

Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice

A Fluorescent Probe to Unravel Functional Features of Cannabinoid Receptor CB1 in Human Blood and Tonsil Immune System Cells

New Synthetic Inhibitors of Fatty Acid Synthase with Anticancer Activity

Therapeutic perspectives of inhibitors of endocannabinoid degradation

CB1 and CB2 cannabinoid receptor binding studies based on modeling and mutagenesis approaches

Activation of the endocannabinoid system as therapeutic approach in a murine model of multiple sclerosis

New Inhibitors of Angiogenesis with Antitumor Activity in Vivo

Structure–Activity Relationship of a New Series of Reversible Dual Monoacylglycerol Lipase/Fatty Acid Amide Hydrolase Inhibitors

Inside Cover: A Reversible and Selective Inhibitor of Monoacylglycerol Lipase Ameliorates Multiple Sclerosis (Angew. Chem. Int. Ed. 50/2014)

Development of Endocannabinoid-Based Chemical Probes for the Study of Cannabinoid Receptors

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