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Novel diindolylmethane derivatives based NLC formulations to improve the oral bioavailability and anticancer effects in triple negative breast cancer

European journal of pharmaceutics and biopharmaceutics, 2016-11, Vol.108, p.168-179

2016

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Unifying mechanisms of action of the anticancer activities of triterpenoids and synthetic analogs

Anti-cancer agents in medicinal chemistry, 2012-12, Vol.12 (10), p.1211-1220

2012

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Omeprazole Inhibits Pancreatic Cancer Cell Invasion through a Nongenomic Aryl Hydrocarbon Receptor Pathway

Chemical research in toxicology, 2015-05, Vol.28 (5), p.907-918

2015

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Toxicological and pathophysiological roles of reactive oxygen and nitrogen species

Toxicology (Amsterdam), 2010-10, Vol.276 (2), p.85-94

2010

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Structure‐dependent activation of gene expression by bis‐indole and quinoline‐derived activators of nuclear receptor 4A2

Chemical biology & drug design, 2019-10, Vol.94 (4), p.1711-1720

2019

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Structure-dependent inhibition of bladder and pancreatic cancer cell growth by 2-substituted glycyrrhetinic and ursolic acid derivatives

Bioorganic & medicinal chemistry, 2008-04, Vol.18 (8), p.2633-2639

2008

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Isoflavones as Ah Receptor Agonists in Colon-Derived Cell Lines: Structure–Activity Relationships

Chemical research in toxicology, 2019-11, Vol.32 (11), p.2353-2364

2019

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Natural Products as Mechanism-based Anticancer Agents: Sp Transcription Factors as Targets

Phytotherapy research, 2016-11, Vol.30 (11), p.1723-1732

2016

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2,3,7,8-Tetrachlorodibenzo-p-dioxin has both pro-carcinogenic and anti-carcinogenic effects on neuroendocrine prostate carcinoma formation in TRAMP mice

Toxicology and applied pharmacology, 2016-08, Vol.305, p.242-249

2016

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Endocrine disruptors and human health: is there a problem

Toxicology (Amsterdam), 2004-12, Vol.205 (1), p.3-10

SAFE, Stephen

2004

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Transcription factor Sp1, also known as specificity protein 1 as a therapeutic target

Expert opinion on therapeutic targets, 2014-07, Vol.18 (7), p.759-769

2014

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Modulation of gene expression and endocrine response pathways by 2,3,7,8-tetrachlorodibenzo- p-dioxin and related compounds

Pharmacology & therapeutics (Oxford), 1995, Vol.67 (2), p.247-281

Safe, Stephen H.

1995

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Structure-dependent activation of NR4A2 (Nurr1) by 1,1-bis(3′-indolyl)-1-(aromatic)methane analogs in pancreatic cancer cells

Biochemical pharmacology, 2012-05, Vol.83 (10), p.1445-1455

2012

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The Role of Self-Nanoemulsifying Drug Delivery Systems of CDODA-Me in Sensitizing Erlotinib-Resistant Non–Small Cell Lung Cancer

Journal of pharmaceutical sciences, 2020-06, Vol.109 (6), p.1867-1882

2020

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Cobaltous chloride and hypoxia inhibit aryl hydrocarbon receptor-mediated responses in breast cancer cells

Toxicology and applied pharmacology, 2007-08, Vol.223 (1), p.28-38

2007

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Interactions between hormones and chemicals in breast cancer

Annual review of pharmacology and toxicology, 1998-01, Vol.38 (1), p.121-158

Safe, S H

1998

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Inactivation of the orphan nuclear receptor NR4A1 contributes to apoptosis induction by fangchinoline in pancreatic cancer cells

Toxicology and applied pharmacology, 2017-10, Vol.332, p.32-39

2017

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Structure-activity relationships among mono- and dihydroxy flavones as aryl hydrocarbon receptor (AhR) agonists or antagonists in CACO2 cells

Chemico-biological interactions, 2022-09, Vol.365, p.110067-110067, Article 110067

2022

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TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) induces depression-like phenotype

Neurotoxicology (Park Forest South), 2024-07, Vol.103, p.71-77

2024

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Targeting NR4A1 (TR3) in cancer cells and tumors

Expert opinion on therapeutic targets, 2011-02, Vol.15 (2), p.195-206

2011

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The 2022 world health organization reevaluation of human and mammalian toxic equivalency factors for polychlorinated dioxins, dibenzofurans and biphenyls

Regulatory toxicology and pharmacology, 2024-01, Vol.146, p.105525-105525, Article 105525

2024

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The role of xenoestrogenic compounds in the development of breast cancer

Trends in pharmacological sciences (Regular ed.), 2006-08, Vol.27 (8), p.447-454

2006

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Inhibition of CYP1A1-Dependent Activity by the Polynuclear Aromatic Hydrocarbon (PAH) Fluoranthene

Biochemical pharmacology, 1998-03, Vol.55 (6), p.831-839

1998

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Evaluation of Spray BIO-Max DIM-P in Dogs for Oral Bioavailability and in Nu/nu Mice Bearing Orthotopic/Metastatic Lung Tumor Models for Anticancer Activity

Pharmaceutical research, 2015-07, Vol.32 (7), p.2292-2300

2015

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Evaluation of self-emulsified DIM-14 in dogs for oral bioavailability and in Nu/nu mice bearing stem cell lung tumor models for anticancer activity

Journal of controlled release, 2015-09, Vol.213, p.18-26

2015

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Novel diindolylmethane derivatives based NLC formulations to improve the oral bioavailability and anticancer effects in triple negative breast cancer

Unifying mechanisms of action of the anticancer activities of triterpenoids and synthetic analogs

Omeprazole Inhibits Pancreatic Cancer Cell Invasion through a Nongenomic Aryl Hydrocarbon Receptor Pathway

Toxicological and pathophysiological roles of reactive oxygen and nitrogen species

Structure‐dependent activation of gene expression by bis‐indole and quinoline‐derived activators of nuclear receptor 4A2

Structure-dependent inhibition of bladder and pancreatic cancer cell growth by 2-substituted glycyrrhetinic and ursolic acid derivatives

Isoflavones as Ah Receptor Agonists in Colon-Derived Cell Lines: Structure–Activity Relationships

Natural Products as Mechanism-based Anticancer Agents: Sp Transcription Factors as Targets

2,3,7,8-Tetrachlorodibenzo-p-dioxin has both pro-carcinogenic and anti-carcinogenic effects on neuroendocrine prostate carcinoma formation in TRAMP mice

Endocrine disruptors and human health: is there a problem

Transcription factor Sp1, also known as specificity protein 1 as a therapeutic target

Modulation of gene expression and endocrine response pathways by 2,3,7,8-tetrachlorodibenzo- p-dioxin and related compounds

Structure-dependent activation of NR4A2 (Nurr1) by 1,1-bis(3′-indolyl)-1-(aromatic)methane analogs in pancreatic cancer cells

The Role of Self-Nanoemulsifying Drug Delivery Systems of CDODA-Me in Sensitizing Erlotinib-Resistant Non–Small Cell Lung Cancer

Cobaltous chloride and hypoxia inhibit aryl hydrocarbon receptor-mediated responses in breast cancer cells

Interactions between hormones and chemicals in breast cancer

Inactivation of the orphan nuclear receptor NR4A1 contributes to apoptosis induction by fangchinoline in pancreatic cancer cells

Structure-activity relationships among mono- and dihydroxy flavones as aryl hydrocarbon receptor (AhR) agonists or antagonists in CACO2 cells

TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) induces depression-like phenotype

Targeting NR4A1 (TR3) in cancer cells and tumors

The 2022 world health organization reevaluation of human and mammalian toxic equivalency factors for polychlorinated dioxins, dibenzofurans and biphenyls

The role of xenoestrogenic compounds in the development of breast cancer

Inhibition of CYP1A1-Dependent Activity by the Polynuclear Aromatic Hydrocarbon (PAH) Fluoranthene

Evaluation of Spray BIO-Max DIM-P in Dogs for Oral Bioavailability and in Nu/nu Mice Bearing Orthotopic/Metastatic Lung Tumor Models for Anticancer Activity

Evaluation of self-emulsified DIM-14 in dogs for oral bioavailability and in Nu/nu mice bearing stem cell lung tumor models for anticancer activity

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