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Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target

Archives of toxicology, 2017-07, Vol.91 (7), p.2497-2513

2017

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Metformin-induced anticancer activities: recent insights

Biological chemistry, 2018-03, Vol.399 (4), p.321

2018

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Sp transcription factor family and its role in cancer

European journal of cancer (1990), 2005-11, Vol.41 (16), p.2438-2448

2005

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Novel diindolylmethane derivatives based NLC formulations to improve the oral bioavailability and anticancer effects in triple negative breast cancer

European journal of pharmaceutics and biopharmaceutics, 2016-11, Vol.108, p.168-179

2016

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Flavonoids: structure–function and mechanisms of action and opportunities for drug development

한국독성학회지, 2021, 37(2), , pp.147-162

2021

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Unifying mechanisms of action of the anticancer activities of triterpenoids and synthetic analogs

Anti-cancer agents in medicinal chemistry, 2012-12, Vol.12 (10), p.1211

2012

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Diindolylmethane and its halogenated derivatives induce protective autophagy in human prostate cancer cells via induction of the oncogenic protein AEG-1 and activation of AMP-activated protein kinase (AMPK)

Cellular signalling, 2017-12, Vol.40, p.172-182

2017

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Omeprazole Inhibits Pancreatic Cancer Cell Invasion through a Nongenomic Aryl Hydrocarbon Receptor Pathway

Chemical research in toxicology, 2015-05, Vol.28 (5), p.907-918

2015

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The aryl hydrocarbon receptor (AhR) as a drug target for cancer chemotherapy

Current opinion in toxicology, 2017-02, Vol.2, p.24-29

2017

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Pharmacological activation of Nr4a rescues age-associated memory decline

Neurobiology of aging, 2020-01, Vol.85, p.140-144

2020

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Structure‐dependent activation of gene expression by bis‐indole and quinoline‐derived activators of nuclear receptor 4A2

Chemical biology & drug design, 2019-10, Vol.94 (4), p.1711-1720

2019

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Isoflavones as Ah Receptor Agonists in Colon-Derived Cell Lines: Structure–Activity Relationships

Chemical research in toxicology, 2019-11, Vol.32 (11), p.2353-2364

2019

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Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth

Experimental cell research, 2010-08, Vol.316 (13), p.2174-2188

2010

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The Bioactive Compounds [alpha]-Chaconine and Gallic Acid in Potato Extracts Decrease Survival and Induce Apoptosis in LNCaP and PC3 Prostate Cancer Cells

Nutrition and cancer, 2010-07, Vol.62 (5), p.601

2010

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Natural Products as Mechanism-based Anticancer Agents: Sp Transcription Factors as Targets

Phytotherapy research, 2016-11, Vol.30 (11), p.1723-1732

2016

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The drug resistance suppression induced by curcuminoids in colon cancer SW-480 cells is mediated by reactive oxygen species-induced disruption of the microRNA-27a-ZBTB10-Sp axis

Molecular nutrition & food research, 2013-09, Vol.57 (9), p.1638-1648

2013

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Absorption and Biological Activity of Phytochemical-Rich Extracts from Acai (Euterpe oleracea Mart.) Pulp and Oil in Vitro

Journal of agricultural and food chemistry, 2008-05, Vol.56 (10), p.3593-3600

2008

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A novel diindolylmethane analog, 1,1-bis(3’-indolyl)-1-(p-chlorophenyl) methane, inhibits the tumor necrosis factor-induced inflammatory response in primary murine synovial fibroblasts through a Nurr1-dependent mechanism

Molecular immunology, 2018-09, Vol.101, p.46-54

2018

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2,3,7,8-Tetrachlorodibenzo-p-dioxin has both pro-carcinogenic and anti-carcinogenic effects on neuroendocrine prostate carcinoma formation in TRAMP mice

Toxicology and applied pharmacology, 2016-08, Vol.305, p.242-249

2016

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Mechanistic relationships between hepatic genotoxicity and carcinogenicity in male B6C3F1 mice treated with polycyclic aromatic hydrocarbon mixtures

Archives of toxicology, 2015-06, Vol.89 (6), p.967-977

2015

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Induction of apoptosis and nonsteroidal anti-inflammatory drug-activated gene 1 in pancreatic cancer cells by a glycyrrhetinic acid derivative

Molecular carcinogenesis, 2009-08, Vol.48 (8), p.692-702

2009

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CDODA-Me decreases specificity protein transcription factors and induces apoptosis in bladder cancer cells through induction of reactive oxygen species

Urologic oncology, 2016-08, Vol.34 (8), p.337.e11-337.e18

2016

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Theranostic tumor homing nanocarriers for the treatment of lung cancer

Nanomedicine, 2014-07, Vol.10 (5), p.e1053-e1063

2014

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Reactive Oxygen Species and Colorectal Cancer

Current colorectal cancer reports, 2013-12, Vol.9 (4), p.350-357

2013

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Cancer chemotherapy with indole-3-carbinol, bis(3′-indolyl)methane and synthetic analogs

Cancer letters, 2008-10, Vol.269 (2), p.326-338

2008

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Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target

Metformin-induced anticancer activities: recent insights

Sp transcription factor family and its role in cancer

Novel diindolylmethane derivatives based NLC formulations to improve the oral bioavailability and anticancer effects in triple negative breast cancer

Flavonoids: structure–function and mechanisms of action and opportunities for drug development

Unifying mechanisms of action of the anticancer activities of triterpenoids and synthetic analogs

Diindolylmethane and its halogenated derivatives induce protective autophagy in human prostate cancer cells via induction of the oncogenic protein AEG-1 and activation of AMP-activated protein kinase (AMPK)

Omeprazole Inhibits Pancreatic Cancer Cell Invasion through a Nongenomic Aryl Hydrocarbon Receptor Pathway

The aryl hydrocarbon receptor (AhR) as a drug target for cancer chemotherapy

Pharmacological activation of Nr4a rescues age-associated memory decline

Structure‐dependent activation of gene expression by bis‐indole and quinoline‐derived activators of nuclear receptor 4A2

Isoflavones as Ah Receptor Agonists in Colon-Derived Cell Lines: Structure–Activity Relationships

Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth

The Bioactive Compounds [alpha]-Chaconine and Gallic Acid in Potato Extracts Decrease Survival and Induce Apoptosis in LNCaP and PC3 Prostate Cancer Cells

Natural Products as Mechanism-based Anticancer Agents: Sp Transcription Factors as Targets

The drug resistance suppression induced by curcuminoids in colon cancer SW-480 cells is mediated by reactive oxygen species-induced disruption of the microRNA-27a-ZBTB10-Sp axis

Absorption and Biological Activity of Phytochemical-Rich Extracts from Acai (Euterpe oleracea Mart.) Pulp and Oil in Vitro

A novel diindolylmethane analog, 1,1-bis(3’-indolyl)-1-(p-chlorophenyl) methane, inhibits the tumor necrosis factor-induced inflammatory response in primary murine synovial fibroblasts through a Nurr1-dependent mechanism

2,3,7,8-Tetrachlorodibenzo-p-dioxin has both pro-carcinogenic and anti-carcinogenic effects on neuroendocrine prostate carcinoma formation in TRAMP mice

Mechanistic relationships between hepatic genotoxicity and carcinogenicity in male B6C3F1 mice treated with polycyclic aromatic hydrocarbon mixtures

Induction of apoptosis and nonsteroidal anti-inflammatory drug-activated gene 1 in pancreatic cancer cells by a glycyrrhetinic acid derivative

CDODA-Me decreases specificity protein transcription factors and induces apoptosis in bladder cancer cells through induction of reactive oxygen species

Theranostic tumor homing nanocarriers for the treatment of lung cancer

Reactive Oxygen Species and Colorectal Cancer

Cancer chemotherapy with indole-3-carbinol, bis(3′-indolyl)methane and synthetic analogs

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