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Meta-analysis of hepatic cytochrome P450 ontogeny to underwrite the prediction of pediatric pharmacokinetics using physiologically based pharmacokinetic modeling

Journal of clinical pharmacology, 2016-03, Vol.56 (3), p.266-283

2016

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Autosomal Dominant Myopathy: Missense Mutation (Gly-706 → Lys) in the Myosin Heavy Chain IIa Gene

Proceedings of the National Academy of Sciences - PNAS, 2000-12, Vol.97 (26), p.14614-14619

2000

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Tolerability and efficacy of the monoaminergic stabilizer (−)-OSU6162 (PNU-96391A) in Huntington’s disease: a double-blind cross-over study

Acta neuropsychiatrica, 2014-10, Vol.26 (5), p.298-306

2014

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Absorption, Distribution, Metabolism, and Excretion of [ 14 C]-Sotorasib in Rats and Dogs: Interspecies Differences in Absorption, Protein Conjugation and Metabolism

Drug metabolism and disposition, 2022-05, Vol.50 (5), p.600-612

2022

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Analysis of Chromosome 5q31–32 and Psoriasis: Confirmation of a Susceptibility Locus but no Association with SNPs within SLC22A4 and SLC22A5

Journal of investigative dermatology, 2006-05, Vol.126 (5), p.998-1002

2006

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A mutation in POLE predisposing to a multi-tumour phenotype

International journal of oncology, 2014-07, Vol.45 (1), p.77-81

2014

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Selection of alternative CYP3A4 probe substrates for clinical drug interaction studies using in vitro data and in vivo simulation

Drug metabolism and disposition, 2010-06, Vol.38 (6), p.981-987

2010

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Psoriasis susceptibility locus in chromosome region 3q21 identified in patients from southwest Sweden

European journal of human genetics : EJHG, 1999-10, Vol.7 (7), p.783-790

1999

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Strain-Dependent Variability of Early Discovery Small Molecule Pharmacokinetics in Mice: Does Strain Matter?

Drug metabolism and disposition, 2020-08, Vol.48 (8), p.613-621

2020

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Familial Dyslexia in a Large Swedish Family: A Whole Genome Linkage Scan

Behavior genetics, 2011, Vol.41 (1), p.43-49

2011

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Prediction of CYP2D6 drug interactions from in vitro data: evidence for substrate-dependent inhibition

Drug metabolism and disposition, 2012-01, Vol.40 (1), p.47-53

2012

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Evaluation of CYP2C8 inhibition in vitro: utility of montelukast as a selective CYP2C8 probe substrate

Drug metabolism and disposition, 2011-09, Vol.39 (9), p.1546-1554

2011

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CYP2C19 inhibition: the impact of substrate probe selection on in vitro inhibition profiles

Drug metabolism and disposition, 2008-03, Vol.36 (3), p.523-528

2008

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Searching for genes influencing a complex disease: the case of coeliac disease

European journal of human genetics : EJHG, 2008-05, Vol.16 (5), p.542-553

2008

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Evaluation of levocetirizine in beagle dog and cynomolgus monkey telemetry assays: Defining the no QTc effect profile by timepoint and concentration‐QTc analysis

Clinical and translational science, 2023-03, Vol.16 (3), p.436-446

2023

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CYP2C9 inhibition: impact of probe selection and pharmacogenetics on in vitro inhibition profiles

Drug metabolism and disposition, 2006-12, Vol.34 (12), p.1966-1975

2006

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T-cell expansions with conserved T-cell receptor β chain motifs in the peripheral blood of HLA-DRB10401 positive patients with necrotizing vasculitis

Blood, 1998-11, Vol.92 (10), p.3737-3744

1998

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Opinion on Directive 98/44/EC on the legal protection of biotechnical inventions, and its implementation in Sweden

Science and engineering ethics, 2005-01, Vol.11 (1), p.113-115

Wahlstrom, Jan

2005

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Application of cytochrome P450 drug interaction screening in drug discovery

Combinatorial chemistry & high throughput screening, 2010-02, Vol.13 (2), p.145-158

2010

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Evaluation of drug‐drug interaction potential between omecamtiv mecarbil and rosuvastatin, a BCRP substrate, with a clinical study in healthy subjects and using a physiologically‐based pharmacokinetic model

Clinical and translational science, 2021-11, Vol.14 (6), p.2510-2520

2021

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Clinical manifestations of intermediate allele carriers in Huntington disease

Neurology, 2016-08, Vol.87 (6), p.571-578

2016

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Mechanism-based inactivation of cytochrome P450 3A4 by mibefradil through heme destruction

Drug metabolism and disposition, 2011-07, Vol.39 (7), p.1188-1195

2011

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In vitro inhibition of multiple cytochrome P450 isoforms by xanthone derivatives from mangosteen extract

Drug metabolism and disposition, 2009-09, Vol.37 (9), p.1848-1855

2009

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The in vitro drug interaction potential of dietary supplements containing multiple herbal components

Drug metabolism and disposition, 2007-02, Vol.35 (2), p.185-188

2007

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Enzyme source effects on CYP2C9 kinetics and inhibition

Drug metabolism and disposition, 2006-11, Vol.34 (11), p.1903-1908

2006

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Meta-analysis of hepatic cytochrome P450 ontogeny to underwrite the prediction of pediatric pharmacokinetics using physiologically based pharmacokinetic modeling

Autosomal Dominant Myopathy: Missense Mutation (Gly-706 → Lys) in the Myosin Heavy Chain IIa Gene

Tolerability and efficacy of the monoaminergic stabilizer (−)-OSU6162 (PNU-96391A) in Huntington’s disease: a double-blind cross-over study

Absorption, Distribution, Metabolism, and Excretion of [ 14 C]-Sotorasib in Rats and Dogs: Interspecies Differences in Absorption, Protein Conjugation and Metabolism

Analysis of Chromosome 5q31–32 and Psoriasis: Confirmation of a Susceptibility Locus but no Association with SNPs within SLC22A4 and SLC22A5

A mutation in POLE predisposing to a multi-tumour phenotype

Selection of alternative CYP3A4 probe substrates for clinical drug interaction studies using in vitro data and in vivo simulation

Psoriasis susceptibility locus in chromosome region 3q21 identified in patients from southwest Sweden

Strain-Dependent Variability of Early Discovery Small Molecule Pharmacokinetics in Mice: Does Strain Matter?

Familial Dyslexia in a Large Swedish Family: A Whole Genome Linkage Scan

Prediction of CYP2D6 drug interactions from in vitro data: evidence for substrate-dependent inhibition

Evaluation of CYP2C8 inhibition in vitro: utility of montelukast as a selective CYP2C8 probe substrate

CYP2C19 inhibition: the impact of substrate probe selection on in vitro inhibition profiles

Searching for genes influencing a complex disease: the case of coeliac disease

Evaluation of levocetirizine in beagle dog and cynomolgus monkey telemetry assays: Defining the no QTc effect profile by timepoint and concentration‐QTc analysis

CYP2C9 inhibition: impact of probe selection and pharmacogenetics on in vitro inhibition profiles

T-cell expansions with conserved T-cell receptor β chain motifs in the peripheral blood of HLA-DRB10401 positive patients with necrotizing vasculitis

Opinion on Directive 98/44/EC on the legal protection of biotechnical inventions, and its implementation in Sweden

Application of cytochrome P450 drug interaction screening in drug discovery

Evaluation of drug‐drug interaction potential between omecamtiv mecarbil and rosuvastatin, a BCRP substrate, with a clinical study in healthy subjects and using a physiologically‐based pharmacokinetic model

Clinical manifestations of intermediate allele carriers in Huntington disease

Mechanism-based inactivation of cytochrome P450 3A4 by mibefradil through heme destruction

In vitro inhibition of multiple cytochrome P450 isoforms by xanthone derivatives from mangosteen extract

The in vitro drug interaction potential of dietary supplements containing multiple herbal components

Enzyme source effects on CYP2C9 kinetics and inhibition

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