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Simvastatin increases the in vivo activity of the first-line tuberculosis regimen

Journal of antimicrobial chemotherapy, 2014-09, Vol.69 (9), p.2453-2457

2014

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Metformin Adjunctive Therapy Does Not Improve the Sterilizing Activity of the First-Line Antitubercular Regimen in Mice

Antimicrobial agents and chemotherapy, 2017-08, Vol.61 (8)

2017

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Statin adjunctive therapy shortens the duration of TB treatment in mice

Journal of antimicrobial chemotherapy, 2016-06, Vol.71 (6), p.1570-1577

2016

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Reduced Emergence of Isoniazid Resistance with Concurrent Use of Thioridazine against Acute Murine Tuberculosis

Antimicrobial agents and chemotherapy, 2014-07, Vol.58 (7), p.4048-4053

2014

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Biphasic Kill Curve of Isoniazid Reveals the Presence of Drug-Tolerant, Not Drug-Resistant, Mycobacterium tuberculosis in the Guinea Pig

The Journal of infectious diseases, 2009-10, Vol.200 (7), p.1136-1143

2009

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Sterilizing activity of thioridazine in combination with the first-line regimen against acute murine tuberculosis

Antimicrobial agents and chemotherapy, 2014-09, Vol.58 (9), p.5567-5569

2014

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Albumin fusion with granulocyte-macrophage colony-stimulating factor acts as an immunotherapy against chronic tuberculosis

Cellular & molecular immunology, 2021-10, Vol.18 (10), p.2393-2401

2021

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Antibiotic Treatment Shapes the Antigenic Environment During Chronic TB Infection, Offering Novel Targets for Therapeutic Vaccination

Frontiers in immunology, 2020-04, Vol.11, p.680-680

2020

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Fatty acid synthase inhibition activates AMP-activated protein kinase in SKOV3 human ovarian cancer cells

Cancer research (Chicago, Ill.), 2007-04, Vol.67 (7), p.2964-2971

2007

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Potent Rifamycin-Sparing Regimen Cures Guinea Pig Tuberculosis as Rapidly as the Standard Regimen

Antimicrobial Agents and Chemotherapy, 2013-08, Vol.57 (8), p.3910-3916

2013

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C75, a Fatty Acid Synthase Inhibitor, Reduces Food Intake via Hypothalamic AMP-activated Protein Kinase

The Journal of biological chemistry, 2004-05, Vol.279 (19), p.19970-19976

2004

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Intranasal Immunization with DnaK Protein Induces Protective Mucosal Immunity against Tuberculosis in CD4-Depleted Mice

Frontiers in cellular and infection microbiology, 2018-02, Vol.8, p.31-31

2018

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Rifapentine Is Not More Active than Rifampin against Chronic Tuberculosis in Guinea Pigs

Antimicrobial Agents and Chemotherapy, 2012-07, Vol.56 (7), p.3726-3731

2012

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Thioridazine lacks bactericidal activity in an animal model of extracellular tuberculosis

Journal of antimicrobial chemotherapy, 2013-06, Vol.68 (6), p.1327-1330

2013

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Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells

Cancer research (Chicago, Ill.), 2003-11, Vol.63 (21), p.7330-7337

2003

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Comparison of the ‘Denver regimen’ against acute tuberculosis in the mouse and guinea pig

Journal of antimicrobial chemotherapy, 2010-04, Vol.65 (4), p.729-734

2010

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Application of a Flexible Synthesis of (5R)-Thiolactomycin To Develop New Inhibitors of Type I Fatty Acid Synthase

Journal of medicinal chemistry, 2005-02, Vol.48 (4), p.946-961

2005

Volltextzugriff (PDF)

Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts

Cancer research (Chicago, Ill.), 2000-01, Vol.60 (2), p.213-218

2000

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Vaccination with recombinant Mycobacterium tuberculosis PknD attenuates bacterial dissemination to the brain in guinea pigs

PloS one, 2013-06, Vol.8 (6), p.e66310-e66310

2013

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Effectiveness of tuberculosis chemotherapy correlates with resistance to Mycobacterium tuberculosis infection in animal models

Journal of antimicrobial chemotherapy, 2011-07, Vol.66 (7), p.1560-1566

2011

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Increased Fatty Acid Synthase is a Therapeutic Target in Mesothelioma

Clinical cancer research, 2001-01, Vol.7 (1), p.153-157

2001

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C75 Alters Central and Peripheral Gene Expression to Reduce Food Intake and Increase Energy Expenditure

Endocrinology (Philadelphia), 2005-01, Vol.146 (1), p.486-493

2005

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Fatty Acid Synthase Inhibition in Human Breast Cancer Cells Leads to Malonyl-CoA-Induced Inhibition of Fatty Acid Oxidation and Cytotoxicity

Biochemical and biophysical research communications, 2001-07, Vol.285 (2), p.217-223

2001

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The potent bactericidal activity of streptomycin in the guinea pig model of tuberculosis ceases due to the presence of persisters

Journal of antimicrobial chemotherapy, 2010-10, Vol.65 (10), p.2172-2175

2010

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High Systemic Exposure of Pyrazinoic Acid Has Limited Antituberculosis Activity in Murine and Rabbit Models of Tuberculosis

Antimicrobial agents and chemotherapy, 2016-07, Vol.60 (7), p.4197-4205

2016

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Simvastatin increases the in vivo activity of the first-line tuberculosis regimen

Metformin Adjunctive Therapy Does Not Improve the Sterilizing Activity of the First-Line Antitubercular Regimen in Mice

Statin adjunctive therapy shortens the duration of TB treatment in mice

Reduced Emergence of Isoniazid Resistance with Concurrent Use of Thioridazine against Acute Murine Tuberculosis

Biphasic Kill Curve of Isoniazid Reveals the Presence of Drug-Tolerant, Not Drug-Resistant, Mycobacterium tuberculosis in the Guinea Pig

Sterilizing activity of thioridazine in combination with the first-line regimen against acute murine tuberculosis

Albumin fusion with granulocyte-macrophage colony-stimulating factor acts as an immunotherapy against chronic tuberculosis

Antibiotic Treatment Shapes the Antigenic Environment During Chronic TB Infection, Offering Novel Targets for Therapeutic Vaccination

Fatty acid synthase inhibition activates AMP-activated protein kinase in SKOV3 human ovarian cancer cells

Potent Rifamycin-Sparing Regimen Cures Guinea Pig Tuberculosis as Rapidly as the Standard Regimen

C75, a Fatty Acid Synthase Inhibitor, Reduces Food Intake via Hypothalamic AMP-activated Protein Kinase

Intranasal Immunization with DnaK Protein Induces Protective Mucosal Immunity against Tuberculosis in CD4-Depleted Mice

Rifapentine Is Not More Active than Rifampin against Chronic Tuberculosis in Guinea Pigs

Thioridazine lacks bactericidal activity in an animal model of extracellular tuberculosis

Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells

Comparison of the ‘Denver regimen’ against acute tuberculosis in the mouse and guinea pig

Application of a Flexible Synthesis of (5R)-Thiolactomycin To Develop New Inhibitors of Type I Fatty Acid Synthase

Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts

Vaccination with recombinant Mycobacterium tuberculosis PknD attenuates bacterial dissemination to the brain in guinea pigs

Effectiveness of tuberculosis chemotherapy correlates with resistance to Mycobacterium tuberculosis infection in animal models

Increased Fatty Acid Synthase is a Therapeutic Target in Mesothelioma

C75 Alters Central and Peripheral Gene Expression to Reduce Food Intake and Increase Energy Expenditure

Fatty Acid Synthase Inhibition in Human Breast Cancer Cells Leads to Malonyl-CoA-Induced Inhibition of Fatty Acid Oxidation and Cytotoxicity

The potent bactericidal activity of streptomycin in the guinea pig model of tuberculosis ceases due to the presence of persisters

High Systemic Exposure of Pyrazinoic Acid Has Limited Antituberculosis Activity in Murine and Rabbit Models of Tuberculosis

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