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NRF2-GPX4/SOD2 axis imparts resistance to EGFR-tyrosine kinase inhibitors in non-small-cell lung cancer cells

Acta pharmacologica Sinica, 2021-04, Vol.42 (4), p.613-623

2021

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Friend or foe： the role of microRNA in chemotherapy resistance

Acta pharmacologica Sinica, 2013-07, Vol.34 (7), p.870-879

2013

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TGFβ2-mediated epithelial-mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance

Acta pharmacologica Sinica, 2021-03, Vol.42 (3), p.451-459

2021

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Increased S1P induces S1PR2 internalization to blunt the sensitivity of colorectal cancer to 5-fluorouracil via promoting intracellular uracil generation

Acta pharmacologica Sinica, 2021-03, Vol.42 (3), p.460-469

2021

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Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma

Acta pharmacologica Sinica, 2021-05, Vol.42 (5), p.814-823

2021

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The role of reduced intracellular concentrations of active drugs in the lack of response to anticancer chemotherapy

Acta pharmacologica Sinica, 2014-01, Vol.35 (1), p.1-10

2014

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Codelivery of dihydroartemisinin and doxorubicin in mannosylated liposomes for drug-resistant colon cancer therapy

Acta pharmacologica Sinica, 2017-06, Vol.38 (6), p.885-896

2017

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KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells

Acta pharmacologica Sinica, 2019-04, Vol.40 (4), p.546-555

2019

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Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations

Acta pharmacologica Sinica, 2024-06, Vol.45 (6), p.1305-1315

2024

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Cathepsin L upregulation-induced EMT phenotype is associated with the acquisition of cisplatin or paclitaxel resistance in A549 cells

Acta pharmacologica Sinica, 2016-12, Vol.37 (12), p.1606-1622

2016

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PPARα agonist fenofibrate relieves acquired resistance to gefitinib in non-small cell lung cancer by promoting apoptosis via PPARα/AMPK/AKT/FoxO1 pathway

Acta pharmacologica Sinica, 2022-01, Vol.43 (1), p.167-176

2022

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Inhibition of AXL enhances chemosensitivity of human ovarian cancer cells to cisplatin via decreasing glycolysis

Acta pharmacologica Sinica, 2021-07, Vol.42 (7), p.1180-1189

2021

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Targeted inhibition of the HNF1A/SHH axis by triptolide overcomes paclitaxel resistance in non-small cell lung cancer

Acta pharmacologica Sinica, 2024-05, Vol.45 (5), p.1060-1076

2024

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Acetyl-11-keto-β-boswellic acid suppresses docetaxel-resistant prostate cancer cells in vitro and in vivo by blocking Akt and Stat3 signaling, thus suppressing chemoresistant stem cell-like properties

Acta pharmacologica Sinica, 2019-05, Vol.40 (5), p.689-698

2019

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Delivery of mitochondriotropic doxorubicin derivatives using self-assembling hyaluronic acid nanocarriers in doxorubicin-resistant breast cancer

Acta pharmacologica Sinica, 2018-10, Vol.39 (10), p.1681-1692

2018

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Brigatinib, a newly discovered AXL inhibitor, suppresses AXL-mediated acquired resistance to osimertinib in EGFR-mutated non-small cell lung cancer

Acta pharmacologica Sinica, 2024-06, Vol.45 (6), p.1264-1275

2024

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Targeting DNA-PK overcomes acquired resistance to third-generation EGFR-TKI osimertinib in non-small-cell lung cancer

Acta pharmacologica Sinica, 2021-04, Vol.42 (4), p.648-654

2021

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SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors

Acta pharmacologica Sinica, 2021-06, Vol.42 (6), p.998-1004

2021

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Cystine supplementation rebalances the redox homeostasis of microenvironment in non-small cell lung cancer cells and reverses their resistance to docetaxel

Acta pharmacologica Sinica, 2021-12, Vol.42 (12), p.2132-2143

2021

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Sirolimus induces apoptosis and reverses multidrug resistance in human osteosarcoma cells in vitro via increasing microRNA-34b expression

Acta pharmacologica Sinica, 2016-04, Vol.37 (4), p.519-529

2016

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Wu-5, a novel USP10 inhibitor, enhances crenolanib-induced FLT3-ITD-positive AML cell death via inhibiting FLT3 and AMPK pathways

Acta pharmacologica Sinica, 2021-04, Vol.42 (4), p.604-612

2021

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Smart nanoparticles improve therapy for drug- resistant tumors by overcoming pathophysiological barriers

Acta pharmacologica Sinica, 2017-01, Vol.38 (1), p.1-8

2017

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HKB99, an allosteric inhibitor of phosphoglycerate mutase 1, suppresses invasive pseudopodia formation and upregulates plasminogen activator inhibitor-2 in erlotinib-resistant non-small cell lung cancer cells

Acta pharmacologica Sinica, 2021-01, Vol.42 (1), p.115-119

2021

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The PI3K/mTOR dual inhibitor BEZ235 suppresses proliferation and migration and reverses multidrug resistance in acute myeloid leukemia

Acta pharmacologica Sinica, 2017-03, Vol.38 (3), p.382-391

2017

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Reversal of paclitaxel resistance in human ovarian cancer cells with redox-responsive micelles consisting of α-tocopheryl succinate-based polyphosphoester copolymers

Acta pharmacologica Sinica, 2017-06, Vol.38 (6), p.859-873

2017

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NRF2-GPX4/SOD2 axis imparts resistance to EGFR-tyrosine kinase inhibitors in non-small-cell lung cancer cells

Friend or foe： the role of microRNA in chemotherapy resistance

TGFβ2-mediated epithelial-mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance

Increased S1P induces S1PR2 internalization to blunt the sensitivity of colorectal cancer to 5-fluorouracil via promoting intracellular uracil generation

Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma

The role of reduced intracellular concentrations of active drugs in the lack of response to anticancer chemotherapy

Codelivery of dihydroartemisinin and doxorubicin in mannosylated liposomes for drug-resistant colon cancer therapy

KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells

Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations

Cathepsin L upregulation-induced EMT phenotype is associated with the acquisition of cisplatin or paclitaxel resistance in A549 cells

PPARα agonist fenofibrate relieves acquired resistance to gefitinib in non-small cell lung cancer by promoting apoptosis via PPARα/AMPK/AKT/FoxO1 pathway

Inhibition of AXL enhances chemosensitivity of human ovarian cancer cells to cisplatin via decreasing glycolysis

Targeted inhibition of the HNF1A/SHH axis by triptolide overcomes paclitaxel resistance in non-small cell lung cancer

Acetyl-11-keto-β-boswellic acid suppresses docetaxel-resistant prostate cancer cells in vitro and in vivo by blocking Akt and Stat3 signaling, thus suppressing chemoresistant stem cell-like properties

Delivery of mitochondriotropic doxorubicin derivatives using self-assembling hyaluronic acid nanocarriers in doxorubicin-resistant breast cancer

Brigatinib, a newly discovered AXL inhibitor, suppresses AXL-mediated acquired resistance to osimertinib in EGFR-mutated non-small cell lung cancer

Targeting DNA-PK overcomes acquired resistance to third-generation EGFR-TKI osimertinib in non-small-cell lung cancer

SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors

Cystine supplementation rebalances the redox homeostasis of microenvironment in non-small cell lung cancer cells and reverses their resistance to docetaxel

Sirolimus induces apoptosis and reverses multidrug resistance in human osteosarcoma cells in vitro via increasing microRNA-34b expression

Wu-5, a novel USP10 inhibitor, enhances crenolanib-induced FLT3-ITD-positive AML cell death via inhibiting FLT3 and AMPK pathways

Smart nanoparticles improve therapy for drug- resistant tumors by overcoming pathophysiological barriers

HKB99, an allosteric inhibitor of phosphoglycerate mutase 1, suppresses invasive pseudopodia formation and upregulates plasminogen activator inhibitor-2 in erlotinib-resistant non-small cell lung cancer cells

The PI3K/mTOR dual inhibitor BEZ235 suppresses proliferation and migration and reverses multidrug resistance in acute myeloid leukemia

Reversal of paclitaxel resistance in human ovarian cancer cells with redox-responsive micelles consisting of α-tocopheryl succinate-based polyphosphoester copolymers

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