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Glucocorticoid receptor control of transcription: precision and plasticity via allostery

Nature reviews. Molecular cell biology, 2017-03, Vol.18 (3), p.159

2017

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Glucocorticoid receptor binds half sites as a monomer and regulates specific target genes

Genome biology, 2014-07, Vol.15 (7), p.418-418, Article 418

2014

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Metabolic gatekeeper function of B-lymphoid transcription factors

Nature (London), 2017-02, Vol.542 (7642), p.479-483

2017

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Glucocorticoid regulation of the circadian clock modulates glucose homeostasis

Proceedings of the National Academy of Sciences - PNAS, 2009-10, Vol.106 (41), p.17582-17587

2009

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Germline signals deploy NHR-49 to modulate fatty-acid β-oxidation and desaturation in somatic tissues of C. elegans

PLoS genetics, 2014-12, Vol.10 (12), p.e1004829-e1004829

2014

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The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals

Nature structural & molecular biology, 2013-07, Vol.20 (7), p.876

2013

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Crosstalk in Inflammation: The Interplay of Glucocorticoid Receptor-Based Mechanisms and Kinases and Phosphatases

Endocrine reviews, 2009-12, Vol.30 (7), p.830-882

2009

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Opposing Chromatin Signals Direct and Regulate the Activity of Lysine Demethylase 4C (KDM4C)

The Journal of biological chemistry, 2016-03, Vol.291 (12), p.6060-6070

2016

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Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (40), p.15858-15863

2007

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Cell- and gene-specific regulation of primary target genes by the androgen receptor

Genes & development, 2007-08, Vol.21 (16), p.2005-2017

2007

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Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor

PLoS genetics, 2007-06, Vol.3 (6), p.e94-e94

2007

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Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans

PLoS biology, 2005-02, Vol.3 (2), p.e53-e53

2005

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Hic-5 is a transcription coregulator that acts before and/or after glucocorticoid receptor genome occupancy in a gene-selective manner

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (11), p.4007-4012

2014

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A Caenorhabditis elegans Nutrient Response System Partially Dependent on Nuclear Receptor NHR-49

Proceedings of the National Academy of Sciences - PNAS, 2005-09, Vol.102 (38), p.13496-13501

2005

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The Mediator subunit MDT-15 confers metabolic adaptation to ingested material

PLoS genetics, 2008-02, Vol.4 (2), p.e1000021

2008

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Sumoylated NHR-25/NR5A regulates cell fate during C. elegans vulval development

PLoS genetics, 2013-12, Vol.9 (12), p.e1003992-e1003992

2013

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Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects

Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (42), p.15675-15680

2006

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naturally occuring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (44), p.17826-17831

2013

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The Glucocorticoid Receptor and the Coregulator Brm Selectively Modulate Each Other's Occupancy and Activity in a Gene-Specific Manner

Molecular and Cellular Biology, 2011-08, Vol.31 (16), p.3267-3276

2011

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Chromatin Immunoprecipitation (ChIP) Scanning Identifies Primary Glucocorticoid Receptor Target Genes

Proceedings of the National Academy of Sciences - PNAS, 2004-11, Vol.101 (44), p.15603-15608

2004

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Non-competitive androgen receptor inhibition in vitro and in vivo

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (17), p.7233-7238

2009

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Circadian Rhythm Gene Period 3 Is an Inhibitor of the Adipocyte Cell Fate

The Journal of biological chemistry, 2011-03, Vol.286 (11), p.9063-9070

2011

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Defects in the C. elegans acyl-CoA synthase, acs-3, and nuclear hormone receptor, nhr-25, cause sensitivity to distinct, but overlapping stresses

PloS one, 2014-03, Vol.9 (3), p.e92552

2014

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Incoherent feed-forward regulatory logic underpinning glucocorticoid receptor action

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (5), p.1964-1969

2013

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Regulatory Actions of Glucocorticoid Hormones: From Organisms to Mechanisms

Advances in experimental medicine and biology, 2015, Vol.872, p.3

2015

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Glucocorticoid receptor control of transcription: precision and plasticity via allostery

Glucocorticoid receptor binds half sites as a monomer and regulates specific target genes

Metabolic gatekeeper function of B-lymphoid transcription factors

Glucocorticoid regulation of the circadian clock modulates glucose homeostasis

Germline signals deploy NHR-49 to modulate fatty-acid β-oxidation and desaturation in somatic tissues of C. elegans

The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals

Crosstalk in Inflammation: The Interplay of Glucocorticoid Receptor-Based Mechanisms and Kinases and Phosphatases

Opposing Chromatin Signals Direct and Regulate the Activity of Lysine Demethylase 4C (KDM4C)

Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids

Cell- and gene-specific regulation of primary target genes by the androgen receptor

Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor

Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans

Hic-5 is a transcription coregulator that acts before and/or after glucocorticoid receptor genome occupancy in a gene-selective manner

A Caenorhabditis elegans Nutrient Response System Partially Dependent on Nuclear Receptor NHR-49

The Mediator subunit MDT-15 confers metabolic adaptation to ingested material

Sumoylated NHR-25/NR5A regulates cell fate during C. elegans vulval development

Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects

naturally occuring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms

The Glucocorticoid Receptor and the Coregulator Brm Selectively Modulate Each Other's Occupancy and Activity in a Gene-Specific Manner

Chromatin Immunoprecipitation (ChIP) Scanning Identifies Primary Glucocorticoid Receptor Target Genes

Non-competitive androgen receptor inhibition in vitro and in vivo

Circadian Rhythm Gene Period 3 Is an Inhibitor of the Adipocyte Cell Fate

Defects in the C. elegans acyl-CoA synthase, acs-3, and nuclear hormone receptor, nhr-25, cause sensitivity to distinct, but overlapping stresses

Incoherent feed-forward regulatory logic underpinning glucocorticoid receptor action

Regulatory Actions of Glucocorticoid Hormones: From Organisms to Mechanisms

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