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Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting

Clinical cancer research, 2006-09, Vol.12 (17), p.5064-5073

2006

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Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition

Molecular cancer therapeutics, 2005-01, Vol.4 (1), p.101-112

2005

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Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair–deficient malignant glioma xenograft

Molecular cancer therapeutics, 2005-09, Vol.4 (9), p.1364-1368

2005

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Nature, 2006-12, Vol.444 (7120), p.756-760

2006

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Increased binding affinity enhances targeting of glioma xenografts by EGFRvIII‐specific scFv

International journal of cancer, 2000-12, Vol.88 (6), p.962-969

2000

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Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumors

Anti-cancer agents in medicinal chemistry, 2011-02, Vol.11 (2), p.202

2011

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Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas

Cancer research (Chicago, Ill.), 1995-07, Vol.55 (14), p.3140-3148

1995

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Methylator resistance mediated by mismatch repair deficiency in a glioblastoma multiforme xenograft

Cancer research (Chicago, Ill.), 1997-07, Vol.57 (14), p.2933-2936

1997

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Activity of temozolomide in the treatment of central nervous system tumor xenografts

Cancer research (Chicago, Ill.), 1995-07, Vol.55 (13), p.2853-2857

1995

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Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts

Cancer research (Chicago, Ill.), 1990-12, Vol.50 (24), p.8017-8022

1990

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Improved xenograft targeting of tumor-specific anti-epidermal growth factor receptor variant III antibody labeled using N-succinimidyl 4-guanidinomethyl-3-iodobenzoate

Nuclear medicine and biology, 2002, Vol.29 (1), p.1-11

2002

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Tumor-specific anti-epidermal growth factor receptor variant III monoclonal antibodies : use of the tyramine-cellobiose radioiodination method enhances cellular retention and uptake in tumor xenografts

Cancer research (Chicago, Ill.), 1995-10, Vol.55 (19), p.4375-4382

1995

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Improved targeting of an anti-epidermal growth factor receptor variant III monoclonal antibody in tumor xenografts after labeling using N-succinimidyl 5-iodo-3-pyridinecarboxylate

Cancer research (Chicago, Ill.), 1997-04, Vol.57 (8), p.1510-1515

1997

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Treatment of Neoplastic Meningitis with Intrathecal Temozolomide

Clinical cancer research, 1999-05, Vol.5 (5), p.1183-1188

1999

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Amplification and expression of the epidermal growth factor receptor gene in human glioma xenografts

Cancer research (Chicago, Ill.), 1988-04, Vol.48 (8), p.2231-2238

1988

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Activity of irofulven (6-hydroxymethylacylfulvene) in the treatment of glioblastoma multiforme-derived xenografts in athymic mice

Cancer chemotherapy and pharmacology, 2001-11, Vol.48 (5), p.413-416

2001

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Activity of 9-dimethylaminomethyl-10-hydroxycamptothecin against pediatric and adult central nervous system tumor xenografts

Cancer chemotherapy and pharmacology, 1994, Vol.34 (2), p.171-174

1994

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Comprehensive molecular cytogenetic investigation of chromosomal abnormalities in human medulloblastoma cell lines and xenograft

Neuro-oncology (Charlottesville, Va.), 2002-04, Vol.4 (2), p.75-85

2002

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Radioiodination via D-amino acid peptide enhances cellular retention and tumor xenograft targeting of an internalizing anti-epidermal growth factor receptor variant III monoclonal antibody

Cancer research (Chicago, Ill.), 2000-08, Vol.60 (16), p.4453-4460

2000

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Activity of intrathecal 4-hydroperoxycyclophosphamide in a nude rat model of human neoplastic meningitis

Cancer research (Chicago, Ill.), 1990-03, Vol.50 (6), p.1954-1959

1990

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Improved therapeutic efficacy of a monoclonal antibody radioiodinated using N-succinimidyl-3-(tri-n-butylstannyl)benzoate

Cancer research (Chicago, Ill.), 1991-08, Vol.51 (16), p.4164-4169

1991

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Intraarterial therapy of human glioma xenografts in athymic rats using 4-hydroperoxycyclophosphamide

Cancer research (Chicago, Ill.), 1993-05, Vol.53 (10), p.2338-2343

1993

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In vivo growth conditions suppress the expression of ganglioside GM2 and favour that of lacto series gangliosides in the human glioma D-54MG cell line

Glycoconjugate journal, 1996-06, Vol.13 (3), p.391-399

1996

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Intrathecal melphalan therapy of human neoplastic meningitis in athymic nude rats

Cancer research (Chicago, Ill.), 1994-09, Vol.54 (17), p.4710-4714

1994

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Comparative localization of murine monoclonal antibody Me1-14 F(ab')2 fragment and whole IgG2a in human glioma xenografts

Cancer research (Chicago, Ill.), 1988-10, Vol.48 (20), p.5701-5707

1988

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KollektionAmerican Association for the Advancement of Science

ThemaTumors Of The Nervous System. Phacomatoses

ThemaTransplantation, Heterologous

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Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting

Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition

Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair–deficient malignant glioma xenograft

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Increased binding affinity enhances targeting of glioma xenografts by EGFRvIII‐specific scFv

Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumors

Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas

Methylator resistance mediated by mismatch repair deficiency in a glioblastoma multiforme xenograft

Activity of temozolomide in the treatment of central nervous system tumor xenografts

Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts

Improved xenograft targeting of tumor-specific anti-epidermal growth factor receptor variant III antibody labeled using N-succinimidyl 4-guanidinomethyl-3-iodobenzoate

Tumor-specific anti-epidermal growth factor receptor variant III monoclonal antibodies : use of the tyramine-cellobiose radioiodination method enhances cellular retention and uptake in tumor xenografts

Improved targeting of an anti-epidermal growth factor receptor variant III monoclonal antibody in tumor xenografts after labeling using N-succinimidyl 5-iodo-3-pyridinecarboxylate

Treatment of Neoplastic Meningitis with Intrathecal Temozolomide

Amplification and expression of the epidermal growth factor receptor gene in human glioma xenografts

Activity of irofulven (6-hydroxymethylacylfulvene) in the treatment of glioblastoma multiforme-derived xenografts in athymic mice

Activity of 9-dimethylaminomethyl-10-hydroxycamptothecin against pediatric and adult central nervous system tumor xenografts

Comprehensive molecular cytogenetic investigation of chromosomal abnormalities in human medulloblastoma cell lines and xenograft

Radioiodination via D-amino acid peptide enhances cellular retention and tumor xenograft targeting of an internalizing anti-epidermal growth factor receptor variant III monoclonal antibody

Activity of intrathecal 4-hydroperoxycyclophosphamide in a nude rat model of human neoplastic meningitis

Improved therapeutic efficacy of a monoclonal antibody radioiodinated using N-succinimidyl-3-(tri-n-butylstannyl)benzoate

Intraarterial therapy of human glioma xenografts in athymic rats using 4-hydroperoxycyclophosphamide

In vivo growth conditions suppress the expression of ganglioside GM2 and favour that of lacto series gangliosides in the human glioma D-54MG cell line

Intrathecal melphalan therapy of human neoplastic meningitis in athymic nude rats

Comparative localization of murine monoclonal antibody Me1-14 F(ab')2 fragment and whole IgG2a in human glioma xenografts

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