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Central Precocious Puberty Caused by Mutations in the Imprinted Gene MKRN3

The New England journal of medicine, 2013-06, Vol.368 (26), p.2467-2475

2013

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MKRN3 inhibits the reproductive axis through actions in kisspeptin-expressing neurons

The Journal of clinical investigation, 2020-08, Vol.130 (8), p.4486-4500

2020

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Hyperoside Ameliorates DSS-Induced Colitis through MKRN1-Mediated Regulation of PPARγ Signaling and Th17/Treg Balance

Journal of agricultural and food chemistry, 2021-12, Vol.69 (50), p.15240-15251

2021

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Lymph-node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: the phase 1 AMPLIFY-201 trial

Nature medicine, 2024-02, Vol.30 (2), p.531-542

2024

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MKRN3-mediated ubiquitination of Poly(A)-binding proteins modulates the stability and translation of GNRH1 mRNA in mammalian puberty

Nucleic acids research, 2021-04, Vol.49 (7), p.3796-3813

2021

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Genotype–Phenotype Correlations in Central Precocious Puberty Caused by MKRN3 Mutations

The journal of clinical endocrinology and metabolism, 2021-04, Vol.106 (4), p.1041-1050

2021

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Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3

PLoS biology, 2019-11, Vol.17 (11), p.e3000532-e3000532

2019

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E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer

The Journal of experimental medicine, 2021-08, Vol.218 (8)

2021

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The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation

Genome Biology, 2019-10, Vol.20 (1), p.216-216, Article 216

2019

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Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation

Nature communications, 2018-08, Vol.9 (1), p.3404-14, Article 3404

2018

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Ubiquitination of IGF2BP3 by E3 ligase MKRN2 regulates the proliferation and migration of human neuroblastoma SHSY5Y cells

Biochemical and biophysical research communications, 2020-08, Vol.529 (1), p.43-50

2020

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Novel MKRN3 Missense Mutations Associated With Central Precocious Puberty Reveal Distinct Effects on Ubiquitination

The journal of clinical endocrinology and metabolism, 2023-07, Vol.108 (7), p.1646-1656

2023

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The rs6576457 G > A variant in the MKRN3 gene promoter significantly increases the risk of central precocious puberty and lung cancer in Hubei Chinese population

Human molecular genetics, 2024-09

2024

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Integrated analysis of exosomal lncRNA and mRNA expression profiles reveals the involvement of lnc‐MKRN2‐42:1 in the pathogenesis of Parkinson's disease

CNS neuroscience & therapeutics, 2020-05, Vol.26 (5), p.527-537

2020

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CircVPS8 promotes the malignant phenotype and inhibits ferroptosis of glioma stem cells by acting as a scaffold for MKRN1, SOX15 and HNF4A

Oncogene, 2024-08, Vol.43 (36), p.2679-2695

2024

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Mouse Testicular Mkrn3 Expression Is Primarily Interstitial, Increases Peripubertally, and Is Responsive to LH/hCG

Endocrinology (Philadelphia), 2023-09, Vol.164 (9), p.1

2023

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Mutations in the maternally imprinted gene MKRN3 are common in familial central precocious puberty

European journal of endocrinology, 2016-01, Vol.174 (1), p.1-8

2016

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Identifying cellular RNA-binding proteins during infection uncovers a role for MKRN2 in influenza mRNA trafficking

PLoS pathogens, 2024-05, Vol.20 (5), p.e1012231-e1012231

2024

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SOH Estimation for Lithium-Ion Batteries Based on Health Indicators Extraction and MKRVR

Journal of the Electrochemical Society, 2024-02, Vol.171 (2), p.20548

2024

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Suppression of PPARγ through MKRN1-mediated ubiquitination and degradation prevents adipocyte differentiation

Cell death and differentiation, 2014-04, Vol.21 (4), p.594-603

2014

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High Frequency of MKRN3 Mutations in Male Central Precocious Puberty Previously Classified as Idiopathic

Neuroendocrinology, 2017-01, Vol.105 (1), p.17-25

2017

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A new pathway in the control of the initiation of puberty: the MKRN3 gene

Journal of molecular endocrinology, 2015-06, Vol.54 (3), p.R131-R139

2015

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Heterozygous Deletions in MKRN3 Cause Central Precocious Puberty Without Prader-Willi Syndrome

The journal of clinical endocrinology and metabolism, 2020-08, Vol.105 (8), p.2732-2739

2020

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MKRN3 circulating levels in girls with central precocious puberty caused by MKRN3 gene mutations

Journal of endocrinological investigation, 2024-06, Vol.47 (6), p.1477-1485

2024

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Circulating MKRN3 Levels Decline Prior to Pubertal Onset and Through Puberty: A Longitudinal Study of Healthy Girls

The journal of clinical endocrinology and metabolism, 2015-05, Vol.100 (5), p.1920-1926

2015

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Central Precocious Puberty Caused by Mutations in the Imprinted Gene MKRN3

MKRN3 inhibits the reproductive axis through actions in kisspeptin-expressing neurons

Hyperoside Ameliorates DSS-Induced Colitis through MKRN1-Mediated Regulation of PPARγ Signaling and Th17/Treg Balance

Lymph-node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: the phase 1 AMPLIFY-201 trial

MKRN3-mediated ubiquitination of Poly(A)-binding proteins modulates the stability and translation of GNRH1 mRNA in mammalian puberty

Genotype–Phenotype Correlations in Central Precocious Puberty Caused by MKRN3 Mutations

Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3

E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer

The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation

Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation

Ubiquitination of IGF2BP3 by E3 ligase MKRN2 regulates the proliferation and migration of human neuroblastoma SHSY5Y cells

Novel MKRN3 Missense Mutations Associated With Central Precocious Puberty Reveal Distinct Effects on Ubiquitination

The rs6576457 G > A variant in the MKRN3 gene promoter significantly increases the risk of central precocious puberty and lung cancer in Hubei Chinese population

Integrated analysis of exosomal lncRNA and mRNA expression profiles reveals the involvement of lnc‐MKRN2‐42:1 in the pathogenesis of Parkinson's disease

CircVPS8 promotes the malignant phenotype and inhibits ferroptosis of glioma stem cells by acting as a scaffold for MKRN1, SOX15 and HNF4A

Mouse Testicular Mkrn3 Expression Is Primarily Interstitial, Increases Peripubertally, and Is Responsive to LH/hCG

Mutations in the maternally imprinted gene MKRN3 are common in familial central precocious puberty

Identifying cellular RNA-binding proteins during infection uncovers a role for MKRN2 in influenza mRNA trafficking

SOH Estimation for Lithium-Ion Batteries Based on Health Indicators Extraction and MKRVR

Suppression of PPARγ through MKRN1-mediated ubiquitination and degradation prevents adipocyte differentiation

High Frequency of MKRN3 Mutations in Male Central Precocious Puberty Previously Classified as Idiopathic

A new pathway in the control of the initiation of puberty: the MKRN3 gene

Heterozygous Deletions in MKRN3 Cause Central Precocious Puberty Without Prader-Willi Syndrome

MKRN3 circulating levels in girls with central precocious puberty caused by MKRN3 gene mutations

Circulating MKRN3 Levels Decline Prior to Pubertal Onset and Through Puberty: A Longitudinal Study of Healthy Girls

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