Details

Autor(en) / Beteiligte

• Yu, Wei
• Hu, Shiyun
• Xu, Xiaoling
• Yan, Jing
• Ding, Fang
• Chen, Xuan
• Su, Meifang
• Lou, Zhenjun
• Zhu, Qiuliang
• Hu, Zhenping
• He, Junfei
• Shao, Jianling
• Zhang, Zugui

Titel

Abstract 15607: Status of Dyslipidemia and Associated Risk Factors in Eastern China

Ist Teil von

• Circulation (New York, N.Y.), 2019-11, Vol.140 (Suppl_1 Suppl 1), p.A15607-A15607

Ort / Verlag

by the American College of Cardiology Foundation and the American Heart Association, Inc

Erscheinungsjahr

2019

Quelle

Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals

Beschreibungen/Notizen

• IntroductionThe prevalence of dyslipidemia continues to increase worldwide, including in China, but recent data are lacking.HypothesisA survey was conducted between 2015 and 2016 to assess the prevalence of dyslipidemia and associated risk factors in Eastern China.MethodsA stratified multistage random sampling method was used toobtain a representative sample of 40751 residents aged 35-75 years from 6 counties/cities in Zhejiang province. Total cholesterol was measured by COD-PAP method, low-density lipoprotein (LDL) and high-density lipoprotein (HDL)cholesterol by homogeneous assays, and triglyceride (TG) levels by GPO-PAP method.Hypercholesterolemia was defined as total cholesterol≥6.20mmol / L; hypertriglyceridemia was defined as TG≥2.3mmol / L; high LDL level ≥2.3mmol / L; and low HDL <1.0mmol / L. Dyslipidemia was defined as hypercholesterolemia or high LDL, or low HDL cholesterol. The prevalence of dyslipidemia was estimated based on the 2016 Chinese Guideline on the Management of Blood Cholesterol.Multivariate logistic regression was used for associated risk factors analysis.ResultsOverall, the prevalence of dyslipidemia was 34.6%, with significant difference between urban and ruralresidents (39.1% versus 36.1%, P< 0.0001).The prevalences of hypercholesterolemia, hypertriglyceridemia, low HDL hyperlipidemia, high LDL hyperlipidemia, and mixed hyperlipidemia were 16.1%, 13.8%, 10.4%,14.5%, and 4.0%, respectively. The prevalences of all subtypes of dyslipidemia, especially hypercholesterolemia and high LDL hyperlipidemia, increased among women aged 50 or older and reached peaksamong men at age 40-55.The risk factors associated with dyslipidemia were increasing age ( age >50, adjusted odds ratio (aOR)2.05, 95% CI1.80-2.32), smoking status (smoker vs non-smoker, aOR1.1295% CI1.05-1.19), obesity status (obesity vs normal, aOR2.11, 96% CI1.97-2.27), hypertension (yes vs no, aOR1.22, 95% CI1.17-1.28), diabetes (yes vs no, aOR1.55, 95% CI1.44-1.66), Hyperuricemia (yes vs no, aOR1.82, 95% CI1.70-1.94),among others.ConclusionsThere is a high prevalence of dyslipidemia in Eastern China.Management strategy ofdyslipidemia needs to improve based on the characteristics of different groups.