Details

Autor(en) / Beteiligte

• Hu, Lin‐Ping
• Zhang, De‐Run
• Liu, Feng‐Lin
• Huang, Xiao‐Hong
• Li, Xia
• Teng, Ming‐Yu
• Liu, Bo
• Huang, Guo‐Li

Titel

Metal‐Free Visible‐Light‐Promoted Haloazidation/Cyclization of Phenyl‐Linked 1,6‐Enynes with TMSN3 and NIS/NBS

Ist Teil von

• ChemistrySelect (Weinheim), 2023-08, Vol.8 (29), p.n/a

Erscheinungsjahr

2023

Quelle

Wiley Online Library - AutoHoldings Journals

Beschreibungen/Notizen

• A metal‐ and oxidant‐free procedure for the three‐component haloazidation/cyclization of phenyl‐linked 1,6‐enynes with TMSN3 and N‐iodo(bromo)succinimide under the irradiation of visible light was described. Moreover, this reaction involved a radical addition/5‐exo‐dig cyclization/radical coupling process, and realized simultaneous construction of C−N, C−C, and C−X (I, Br) bonds in one step. A visible‐light‐promoted three‐component haloazidation/cyclization of phenyl‐linked 1,6‐enynes with TMSN3 and N‐iodo/bromo‐succinimide under metal‐ and oxidant‐free conditions was presented. These methods provide an alternative and facile synthetic route to access a series of haloazidated 2,3‐dihydro‐1H‐indenes in moderate yields. This is a useful, time‐efficient, and scalable procedure for the construction of C−N, C−C, and C−X (I, Br) bonds in one step.