European Journal of Organic Chemistry, 2008, Vol.2008 (5), p.854-861
2008
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- Autor(en) / Beteiligte
- Titel
- Synthesis of (4R,15R,16R,21S)-Rollicosin and Its 4S Epimer
- Ist Teil von
- European Journal of Organic Chemistry, 2008, Vol.2008 (5), p.854-861
- Ort / Verlag
- Weinheim: WILEY-VCH Verlag
- Erscheinungsjahr
- 2008
- Quelle
- Alma/SFX Local Collection
- Beschreibungen/Notizen
- (4R,15R,16R,21S)‐Rollicosin (2) was synthesized by palladium‐catalyzed coupling of two building blocks 4 and 5. Lactone 4 was synthesized from 1‐heptyne and terminal acetylene 5 was prepared from lactone 6 and allyl iodide or (S)‐epichlorohydrin. (4S,15R,16R,21S)‐Rollicosin (3) was also synthesized from (R)‐epichlorohydrin by the same synthetic pathway.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1434-193XeISSN: 1099-0690DOI: 10.1002/ejoc.200700930Titel-ID: cdi_wiley_primary_10_1002_ejoc_200700930_EJOC200700930
- Format
- –
- Schlagworte
- Acetogenins, Anticancer, Configurational determination, Rollicosin, Total synthesis