Details

Autor(en) / Beteiligte

• Zhang, Yanqing
• Chen, Zuliang
• Xiao, Yuanjing
• Zhang, Junliang

Titel

RhI‐Catalyzed Regio‐ and Stereospecific Carbonylation of 1‐(1‐Alkynyl)cyclopropyl Ketones: A Modular Entry to Highly Substituted 5,6‐Dihydrocyclopenta[c]furan‐4‐ones

Ist Teil von

• Chemistry : a European journal, 2009-05, Vol.15 (21), p.5208-5211

Ort / Verlag

Weinheim: WILEY‐VCH Verlag

Erscheinungsjahr

2009

Link zum Volltext

Quelle

Wiley Online Library Journals Frontfile Complete

Beschreibungen/Notizen

• Efficient route: A novel RhI‐catalyzed regio‐ and stereospecific carbonylation reaction of (1‐alkynyl)cyclopropyl ketones by selective activation of a carboncarbon σ bond of the cyclopropane ring was demonstrated (see scheme). This method provides a general, efficient, stereoselective route to synthesise 1,3,5‐trisubstituted and 1,3,5,6‐tetrasubstituted 5,6‐dihydrocyclopenta[c]furan‐4‐one with convertible functional groups. Efficient route: A novel RhI‐catalyzed regio‐ and stereospecific carbonylation reaction of (1‐alkynyl)cyclopropyl ketones by selective activation of a carboncarbon σ bond of the cyclopropane ring was demonstrated (see scheme). This method provides a general, efficient, stereoselective route to synthesise 1,3,5‐trisubstituted and 1,3,5,6‐tetrasubstituted 5,6‐dihydrocyclopenta[c]furan‐4‐one with convertible functional groups.