Details

Autor(en) / Beteiligte

• Ingham, John
• Heinzle, Elmar
• Přenosil, Jiří
• Dunn, Irving J

Titel

Biological Kinetics

Ist Teil von

• Biological Reaction Engineering, 2021, p.57-90

Ort / Verlag

Weinheim, Germany: WILEY‐VCH GmbH

Erscheinungsjahr

2021

Link zum Volltext

Quelle

Wiley Online Library All Obooks

Beschreibungen/Notizen

• In the case of modeling the behavior of enzyme reactors, knowledge of the enzyme reaction kinetics is most important. The sheer complexity of the biological reactions, occurring in a living cell, seems to imply an almost impossible task in obtaining meaningful rate data for biological modeling applications. This chapter introduces some of the most important parts required for setting up and applying enzyme kinetic models in bioreactor simulation. The rate of reaction catalyzed by a soluble enzyme can usually be described by the Michaelis–Menten kinetic equation. Substrate inhibition is often observed in biocatalytic applications of enzymes since high concentrations of substrate are required for process intensification. Many substrates can be utilized by organisms at low concentration, but at high concentrations they can also act as toxic growth inhibitors. Multiple‐organism populations will involve interactions in which one species of organisms will exert some influence on another.