Details

Autor(en) / Beteiligte

• Ponta, Helmut
• Orian‐Rousseau, Véronique
• Groner, Bernd

Titel

Peptides Derived from Exon v6 of the CD44 Extracellular Domain Prevent Activation of Receptor Tyrosine Kinase and Subsequently Angiogenesis and Metastatic Spread of Tumor Cells

Ist Teil von

• Peptides as Drugs, 2009, p.35-55

Ort / Verlag

Weinheim, Germany: Wiley‐VCH Verlag GmbH & Co. KGaA

Erscheinungsjahr

2009

Link zum Volltext

Quelle

Wiley Online Library All Obooks

Beschreibungen/Notizen

• This chapter contains sections titled: Introduction CD44 Proteins and Their Involvement in RTK Activation CD44v6 Acts as a Coreceptor for c‐Met and Ron Three Amino Acids in CD44 Exon v6 Are Crucial for the CD44v6 Coreceptor Function, and Small Peptides Can Interfere with This Function The Ectodomain of CD44v6 Binds to HGF Peptides Corresponding to Exon v6 of CD44 Inhibit Metastatic Spread of Tumor Cells The Significance of the Collaboration between CD44v6 and c‐Met In Vivo The CD44v6 Peptides Interfere with Angiogenesis Outlook References