Details

Autor(en) / Beteiligte

• Domínguez‐Muñoz, J. Enrique

Titel

Management of Pain in Pancreatic Cancer

Ist Teil von

• Clinical Pancreatology for Practising Gastroenterologists and Surgeons, 2021, p.506-513

Ort / Verlag

Chichester, UK: John Wiley & Sons, Ltd

Erscheinungsjahr

2021

Link zum Volltext

Quelle

Wiley Online Library All Obooks

Beschreibungen/Notizen

• Pancreatic cancer has a dismal prognosis. Diagnosis is frequently made in patients with advanced disease, and only a small proportion of patients undergo a potentially curative treatment. Together with jaundice, abdominal pain is the most frequent clinical presentation of pancreatic cancer. Management of pain in patients with pancreatic cancer should begin with the appropriate pain assessment in the context of the other physical and psychological symptoms that are frequently present. Weight loss, malnutrition, sarcopenia, and cachexia are among the major clinical signs of pancreatic cancer. Deficiency of micronutrients and antioxidants also has a negative impact on pain, and pain relief may be difficult to achieve in severely malnourished and cachectic patients with pancreatic cancer. The principles of pancreatic cancer pain therapy involve maximizing analgesia while minimizing adverse side effects. To achieve this, pharmacological, interventional (neurolytic treatment), and other therapies can be used.