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Hyperadrenocorticism and Primary Functioning Adrenal Tumors in Other Species (Excluding Horses and Ferrets)
Ist Teil von
Clinical Endocrinology of Companion Animals, 2013, p.95-99
Ort / Verlag
Chichester, UK: John Wiley & Sons, Ltd
Erscheinungsjahr
2013
Quelle
Wiley Online Library All Obooks
Beschreibungen/Notizen
This chapter discusses pathogenesis, classical signs, diagnosis, and treatment for hyperadrenocorticism and adrenal tumors in pet rodents and birds. Hyperadrenocorticism is an uncommon diagnosis in pet gerbils but is seen in repeatedly bred and aging laboratory gerbils. Adrenocortical adenoma is one of the most common benign neoplasms in the Syrian hamster. Pituitary adenomas are the most commonly reported neuroendocrine tumors in birds. These pituitary tumors are nonfunctional or hypersecrete adrenocorticotropic hormone (ACTH) and be associated with bilateral adrenal hyperplasia. The diagnosis is generally presumed on the basis of history and clinical signs. Mitotane has been suggested as a therapeutic consideration in birds. Necropsy, histopathology, and immunohistochemistry are required for definitive diagnosis. Iatrogenic hyperadrenocorticism is avoided by judicious use of therapeutic corticosteroids in all species.