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Acute exposure to cold or hot ambient conditions elicits various functional and structural changes in the lung. The type and extent of changes vary with the localization and intensity of the thermal stress and between diseased, athletic, and healthy but untrained individuals. Patients with respiratory diseases and elite cold weather athletes are particularly susceptible to the acute effects of cold air breathing. When exposure to the subfreezing conditions is prolonged, more permanent changes may occur within the airways. Warm humid air breathing can have two seemingly opposite effects, especially in individuals with asthma: either preventing exercise‐induced bronchoconstriction or, in the presence of local hyperthermia, triggering a reflex cough and bronchoconstriction.