Details

Autor(en) / Beteiligte

• Lü, You
• Guo, Peng
• Ye, Ying-Jiang
• Wang, Hui
• Shen, Zhan-Long
• Wang, Qi
• Zhao, Chun-Jiang
• Gao, Zhi-Dong
• Zhang, Xin
• Cao, Jian
• Jiang, Ke-Wei
• Wang, Shan

Titel

Clinical and microbiological features of community-acquired and nosocomial bloodstream infections in the surgical department of a tertiary-care hospital in Beijing

Ist Teil von

• Chinese medical journal, 2013-11, Vol.126 (22), p.4242-4246

Ort / Verlag

China: Department of Hepatobiliary Surgery, the First Affiliated Hospital, Shihezi University, Shihezi, Xinjiang 832009, China%Department of Gastroenterological Surgery ,Peking University People's Hospital, Peking University, Beijing 100044, China%Department of Clinical Laboratory ,Peking University People's Hospital, Peking University, Beijing 100044, China

Erscheinungsjahr

2013

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Background Bloodstream infections （BSls） remain a major cause of morbidity and mortality in patients undergoing surgery. This study aimed at elucidating the clinical characteristics of community-acquired BSIs （CABs） and nosocomial BSIs （nBSIs） in patients admitted to the surgical wards of a teaching hospital in Beijing, China. Methods This cross-sectional study compared 191 episodes of BSIs in 4074 patients admitted to the surgical wards between January 2008 and December 2011. Cases of BSIs were classified as CABs or nBSIs, and the characteristics, relevant treatments, and outcomes of CABs and nBSIs were compared. Results Of the 191 BSIs, 52 （27.2%） and 139 （72.8%）were CABs and nBSIs, respectively. Escherichia coli, coagulasenegative staphylococci, and Klebsiella spp, were the most frequently isolated microorganisms. There were significant differences between CABs and nBSIs with respect to the use of hormonal drugs, ventilation, acute physiology and chronic health evaluation （APACHE） Ⅱand American Society of Anesthesiologists scores, and prevalence of cancer （P 〈0.05）. Empirical antibacterial therapy did not decrease the crude mortality, but multivariate analysis showed that high APACHE Ⅱwas independently associated with a risk of mortality （odds ratio =0.97, 95% confidence interval： 0.93-1.02 for APACHE Ⅱ）. Conclusions We found significant differences in the clinical characteristics of surgical patients with CABs and nBSIs. The outcome of patients seems to be related to hiah APACHE Ⅱ scores.