Details

Autor(en) / Beteiligte

• Lu, Ming
• Yao, Wan-zhen
• Zhong, Nan-shan
• Zhou, Yu-min
• Wang, Chen
• Chen, Ping
• Kang, Jian
• Huang, Shao-guang
• Chen, Bao-yuan
• Wang, Chang-zheng
• Ni, Dian-tao
• Wang, Xiao-ping
• Wang, Da-li
• Liu, Sheng-ming
• Lü, Jia-chun
• Shen, Ning
• Ding, Yan-ling
• Ran, Pi-xin

Titel

Asymptomatic patients of chronic obstructive pulmonary disease in China

Ist Teil von

• Chinese medical journal, 2010-06, Vol.123 (12), p.1494-1499

Ort / Verlag

China: Department of Respiratory Medicine, Peking University Third Hospital, Beijing 100191, China%Department of Respiratory Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Diseases,First Affiliated Hospital, Guangzhou Medical University,Guangzhou, Guangdong 510182, China%Department of Respiratory Medicine, Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China%Department of Respiratory Medicine, Shenyang Military General Hospital, Shenyang, Liaoning 110016, China%Department of Respiratory Medicine, First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China%Department of Respiratory Medicine, Ruijin Hospital of Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China%Department of Respiratory Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China%Department of Respiratory Medicine, Xinqiao Hospital of Third Military Medical University, Chongqing 400037, China%Department of Respiratory Medicine, Xijing Hospital of Fourth Military Medical University, Xi'an, Shaanxi 710032, China%Department of Respiratory Medicine, First Municipal People Hospital of Shaoguan, Shaoguan, Guangdong 512000, China%Department of Respiratory Medicine, Second Hospital of Liwan District of Guangzhou, Guangzhou, Guangdong 510160, China%Department of Epidemiology, Guangzhou Medical University,Guangzhou, Guangdong 510182, China

Erscheinungsjahr

2010

Quelle

MEDLINE

Beschreibungen/Notizen

• Background Chronic obstructive pulmonary disease （COPD） has a variable natural history and not all individuals follow the same course. This study aimed to identify the prevalence and characteristics of asymptomatic COPD patients from a population-based survey in China.Methods A multistage cluster sampling strategy was used in a population from seven different provinces/cities. All residents （over 40 years old） were interviewed with a standardized questionnaire and spirometry.Post-bronchodilator forced expiratory volume in 1 second （FEV1）/forced vital capacity （FVC） of less than 70% was defined as the diagnostic criterion of COPD. All COPD patients screened were divided into symptomatic group and asymptomatic group according to the presence or absence of chronic respiratory symptoms. Socio-demographic,personal and exposure variables were collected and analyzed.Results Among the 1668 patients who were diagnosed with COPD from the 25 627 sampling subjects, 589 （35.3%）were asymptomatic. The age, sex, body mass index （BMI）,rural and urban distributions, smoking habit and education levels were similar in the two groups. A total of 64.7% of the asymptomatic patients had no comorbidities. Cardiovascular diseases and lung cancer were more common among symptomatic COPD patients than asymptomatic group.Asymptomatic COPD group were less likely to present with poor ventilation in the kitchen, a family history of respiratory disease and recurrent childhood cough. Asymptomatic COPD patients had significantly higher FEV1 （73.1% vs. 61.0%）, FVC （91.9% vs. 82.0%）, and a higher ratio of FEV1/FVC （62.9% vs.58.7%） （all P 〈0.001） than symptomatic group. More asymptomatic patients were underdiagnosed （91.9% vs.54.3%, P〈0.001） than symptomatic patients.Conclusions This large population-based survey confirmed a high prevalence of asymptomatic COPD patients in China. More use of spirometry screening test may be important to the early detection of COPD.