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Choroidal malignant melanoma in patients with oculodermal melanocytosis: report of three cases
Ist Teil von
Chinese medical journal, 2010-01, Vol.123 (1), p.111-113
Ort / Verlag
China: Eye Center, Beijing Tongren Hospital, Capital Medical University,Beijing 100730, China
Erscheinungsjahr
2010
Quelle
MEDLINE
Beschreibungen/Notizen
Oculodermal melanocytosis (ODM) is a congenital melanocytic pigmentary disorder involving eyetissue. It is a congenital ocular pigmentation with associated melanocytic deposition in the surrounding dermis. In 1939, Ota and Taninol first gave a definitive description of cutaneous hyperpigmentation along the trigeminal nerve distribution in addition to bulbar involvement, called oculodermal melanocytosis (nevus of Ota). Oculodermal melanocytosis is a well-recognized risk factor for the development of choroidal malignant melanoma, especially in white patients. Gonder et al2,3 reported ODM is about 35 times more common in the uveal melanoma population. We report three cases of choroidal malignant melanoma in oculodermal melanocytosis patients.