Details

Autor(en) / Beteiligte

• Huang, Zhi-qiang
• Xu, Li-ning
• Yang, Tao
• Zhang, Wen-zhi
• Huang, Xiao-qiang
• Cai, Shou-wang
• Zhang, Ai-qun
• Feng, Yu-quan
• Zhou, Ning-xin
• Dong, Jia-hong

Titel

Hepatic resection： an analysis of the impact of operative and perioperative factors on morbidity and mortality rates in 2008 consecutive hepatectomy cases

Ist Teil von

• Chinese medical journal, 2009-10, Vol.122 (19), p.2268-2277

Ort / Verlag

China: Institute of Hepatobiliary Surgery, Clinical Division of Surgery, Chinese PLA General Hospital, Beijing 100853, China

Erscheinungsjahr

2009

Quelle

MEDLINE

Beschreibungen/Notizen

• Background Hepatectomy is a standard hepatic surgica line with improvements in surgical techniques. This study with hepatectomy. technique. The safety of hepatectomy has been improved in analyzed the operative and perioperative factors associated Methods A total of 2008 patients who underwent consecutive hepatectomies between January 1986 and December 2005 were investigated retrospectively. Diagnoses were made based on pathological findings. Results Malignant and benign liver diseases accounted for 58.5% and 41.2%, respectively, of the conditions requiring resections. Primary liver cancers accounted for 76.1% of the malignant tumors, while hilar cholangiocarcinomas accounted for 6.7%. Hemangiomas （41.7%） and hepatolithiasis （29.6%） were the most common of the benign conditions. Microwave in-line coagulation was used in 236 of our liver resection cases. The overall postoperative complication rate was 14.44%, of which 12.54% of resections were performed for primary liver cancer, 16.40% for secondary liver cancer, and 16.32% for hepatolithiasis. The overall hospital mortality was 0.55%, and that for malignant liver disease was 0.51%. A high mortality （2.53%） was associated with extensive liver resections for hilar cholangiocarcinomas （two deaths in 79 cases）. Microwave in-line pre-coagulation resection, Child-Pugh grading, operating time, postoperative length of stay, and preoperative serum albumin level were independent predictors of morbidity. Blood loss, Child-Pugh grading, operating time and preoperative serum albumin level were independent predictors of mortality. Conclusions Hepatectomy can be performed safely with low morbidity and mortality, provided that it is carried out with optimal perioperative management and innovative surgical techniques.