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Diffusion tensor imaging on white matter in normal adults and elderly patients with hypertension
Ist Teil von
Chinese medical journal, 2006-08, Vol.119 (15), p.1304-1307
Ort / Verlag
China: Medical Imaging Center, First Affiliated Hospital, Jinan University,Guangzhou 510630, China
Erscheinungsjahr
2006
Quelle
Free E-Journal (出版社公開部分のみ)
Beschreibungen/Notizen
Diffusion-weighted magnetic resonance imaging (MRI) exploits the properties of randomlymoving water molecules in the presence of magnetic field gradients. Within tissue, diffusion of water molecules is restricted by cell membranes, small vessels, axon cylinders, membrane, chemical interactions of water and macromolecules. In the brain, water diffusion exhibits directionality in the orientation along the long axis of white matter. This is referred to as "diffusion anisotropy". Diffusion anisotropy can be measured via diffusion tensor imaging (DTI). There is a class of anisotropy indices that reflect the degree of anisotropy of water diffusion which are related to the degree of architectural and structural coherence within each voxel of the tissue. Fractional anisotropy (FA) was the most frequently used index of anisotropy.