Details

Autor(en) / Beteiligte

• Gu, Jun-chao
• Yu, Wei-bo
• Zhang, Zhong-tao
• Wang, Yu

Titel

A new exploration on the creation of grafted breast cancer model for MA891 cells in TA2 mice

Ist Teil von

• Chinese medical journal, 2005-11, Vol.118 (21), p.1830-1833

Ort / Verlag

China: Department of General Surgery,Beijing Friendship Hospital Affiliated with Capital University of Medical Sciences, Beijing 100050, China

Erscheinungsjahr

2005

Quelle

MEDLINE

Beschreibungen/Notizen

• Animal experimental systems are particularly useful for the study of human breast cancer. An ideal model shoulcl be easy to use, closely mimicking human physiopathology and has a stable tumor morbidity. The cell line MA891 was established from a spontaneous TA2 mouse mammary carcinoma by Cancer Institute of Chinese Academy of Medical Sciences. 3 Some researches indicated that MA891 had a very low immunogenecity and maintained a high metastatic potential in vivo. So it has been used as a better grafted mouse tumor model for studying cancer physiopathology and metastasis in human for years. However, about the biological characteristic and the histopathologic feature of this model there has been a lack of investigations.