Chinese medical journal, 2005-10, Vol.118 (20), p.1742-1745
2005
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Glucocorticoids upregulates transepithelial electrical resistance and expression of tight junction-related protein in human trabecular meshwork cells
- Ist Teil von
- Chinese medical journal, 2005-10, Vol.118 (20), p.1742-1745
- Ort / Verlag
- Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China
- Erscheinungsjahr
- 2005
- Quelle
- Alma/SFX Local Collection
- Beschreibungen/Notizen
- The trabecular meshwork is located at the anterior chamber angle, and is the main route for the outflow of aqueous humor. It is composed of perforated sheets of collagen and elastic tissue covered by trabecular meshwork （TM） cells, forming a filter with decreasing pore size as the canal of Schlemm is approached. TM cells have some endothelial properties, such as the presence of intercellular junctional complexes, particularly tight junctions （TJs）. TJs form paracellular seals between adjacent cells and act as fences that segregate protein （ and partially lipid ） components of the apical and basolateral plasma membrane domains.