Details

Autor(en) / Beteiligte

• Lu, Yun
• Yu, Zhichao
• Yang, Xinan
• Dai, Jingjing
• Shan, Peihui
• Feng, Xianhao
• Tao, Zhu
• Redshaw, Carl
• Xiao, Xin

Titel

Supramolecular assemblies of cucurbit[n]urils and 4-aminopyridine controlled by cucurbit[n]uril size (n = 5, 6, 7 and 8)

Ist Teil von

• Chinese chemical letters, 2023-07, Vol.34 (7), p.108040-136, Article 108040

Ort / Verlag

Elsevier B.V

Erscheinungsjahr

2023

Beschreibungen/Notizen

• The binding interactions between 4-aminopyridine (4-AP) and a series of cucurbit[n]urils (Q[5], Q[6], TMeQ[6], Q[7], Q[8]) have been studied using 1H NMR spectroscopy, UV–vis absorption spectroscopy, isothermal titration calorimetry (ITC) and X-ray crystallography. The data indicates that the Q[5]@4-AP complex exhibits exo binding, which is not observed in the other four host-guest complexes. Furthermore, X-ray crystallography clearly reveals how the Q[n]s bind with 4-AP to form complexes, for example Q[5] forms an outer-surface complex, whilst Q[6], TMeQ[6] and Q[7] formed 1:1 host and guest type complexes, and Q[8] formed a stable 1:2 ternary complex due to its large cavity, which can accommodate two 4-AP molecules. In this work, we have constructed five supramolecular host-guest systems using a series of cucurbit[n]urils (Q[5], Q[6], TMeQ[6], Q[7], Q[8]) and 4-aminopyridine (4-AP). X-ray crystallography clearly reveals how the Q[n]s bind with 4-AP to form complexes, for example Q[5] forms an outer-surface complex, whilst Q[6], TMeQ[6] and Q[7] formed a 1:1 host and guest type complex, and Q[8] formed a stable 1:2 ternary complex due to its large cavity, which can accommodate two 4-AP molecules. [Display omitted]