Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...
A multifunctional upconversion nanoparticles probe for Cu2+ sensing and pattern recognition of biothiols
Ist Teil von
Chinese chemical letters, 2022-08, Vol.33 (8), p.3782-3786
Ort / Verlag
Elsevier B.V
Erscheinungsjahr
2022
Quelle
Elsevier ScienceDirect Journals
Beschreibungen/Notizen
Lanthanide-doped upconversion nanoparticles (Ln-UCNPs) are a new type of nanomaterials with excellent fluorescence properties, which are well applied in fluorescent biosensing. Herein we developed a multifunctional probe based on the surface engineering of core-shell structure UCNPs with polyacrylic acid (PAA). The developed PAA/UCNPs probe could be highly selective to detect and respond to Cu2+ at different pH. Cu2+ could easily combine with the carboxylate anion of PAA to quench the fluorescence of UCNPs. Therefore, we creatively proposed a fluorescent array sensor (PAA/UCNPs-Cu2+), in which the same material acted as the sensing element by coupled with pH regulation for pattern recognition of 5 thiols. It could also easily identify the chiral enantiomer of cystine (l-Cys-and d-Cys), and distinguish their mixed samples with different concentrations, and more importantly, it could be combined with urine samples to detect actual level of homocysteine (Hcys) to provide a new solution for judging whether the human body suffers from homocystinuria.
Herein, we developed a multifunctional probe based on the surface engineering of core-shell structure UCNPs with PAA to versatilely recognize Cu2+ and various metal ions. [Display omitted]