Details

Autor(en) / Beteiligte

• Feng, Xue
• Tian, Jiaxin
• Sun, Ying
• Hu, Huayou
• Lu, Mingzhu
• Kan, Yuhe
• Fang, Danjun
• Wang, Chao

Titel

Weakly coordinating group directed rhodium-catalyzed unconventional site-selective C–H olefination of indolizines at the 8-position

Ist Teil von

• Chinese chemical letters, 2021-01, Vol.32 (1), p.470-474

Ort / Verlag

Elsevier B.V

Erscheinungsjahr

2021

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A rhodium-catalyzed directing group promoted selective C–H olefination reaction of indolizines at the 8-position is reported. Weakly coordinating groups, such as ketone, aldehyde, amide and ester, were used as directing groups. The ester group can be removed under acid conditions and therefore is used as a traceless directing group. [Display omitted] A rhodium-catalyzed directing group promoted selective C–H olefination reaction of indolizines at the 8-position is reported. Di-olefination at 2,8-positions also achieved with silver hexafluoroantimonate as an additive under similar reaction conditions. Weakly coordinating groups, such as ketone, aldehyde, amide and ester, were used as directing groups. The ester group can be removed under acid conditions and therefore is used as a traceless directing group.