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Oxyphyllones A and B, novel sesquiterpenes with an unusual 4,5-secoeudesmane skeleton from Alpinia oxyphylla
Ist Teil von
Chinese chemical letters, 2009-08, Vol.20 (8), p.945-948
Ort / Verlag
Elsevier B.V
Erscheinungsjahr
2009
Link zum Volltext
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
Two novel 4,5-secoeudesmane sesquiterpenoids, oxyphyllones A (
1) and B (
2) were isolated from the fruits of
Alpinia oxyphylla. Their structures were established by spectroscopic methods including 1D and 2D NMR spectra. These two compounds are the first example of naturally occurring sesquiterpenoids with a 4,5-secoeudesmane skeleton in the family of Zingiberaceae and oxyphyllone A (
1) is the first 4,5-secoeudesmane type of 13-norsesquiterpenoid. Compounds
1 and
2 exhibited no cytotoxicities against three cancer cell lines at 10
μg/mL.