Biomedical and environmental sciences, 2017-06, Vol.30 (6), p.455-459
2017
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- Autor(en) / Beteiligte
- Titel
- Serum Fetuin-A Levels and Thyroid Function in Middle-aged and Elderly Chinese
- Ist Teil von
- Biomedical and environmental sciences, 2017-06, Vol.30 (6), p.455-459
- Ort / Verlag
- Elsevier B.V
- Erscheinungsjahr
- 2017
- Quelle
- Alma/SFX Local Collection
- Beschreibungen/Notizen
- Serum fetuin-A levels are reportedly elevated in hyperthyroidism. However, there are few relevant epidemiologic studies. We conducted a cross-sectional study in Songnan community, China in 2009 to investigate the association between serum fetuin-A concentrations and thyroid function. A total of 2,984 participants aged 40 years and older were analyzed. Multivariable linear regression analysis revealed that serum fetuin-A concentra- tions were positively associated with log （free triiodothyronine） and were inversely associated with log （thyroid peroxidase antibody） after adjustment （both P 〈 0.05）. Compared with the participants in the lowest tertile of free triiodo- thyronine and free thyroxine level, those in the highest tertile had higher fetuin-A concentrations. Additionally, high serum fetuin-A concentrations were related to high thyroid function （odds ratio 1.27, 95% confidence interval 1.01-1.61）, after adjustment for conventional risk factors.