Details

Autor(en) / Beteiligte

• Alcaide Martín, María José
• Altimira Queral, Laura
• Sahuquillo Frías, Laura
• Valiña Amado, Laura
• Merino, Anna
• García de Guadiana-Romualdo, Luis

Titel

Automated cell count in body fluids: a review

Ist Teil von

• Advances in Laboratory Medicine / Avances en Medicina de Laboratorio, 2021-06, Vol.2 (2), p.149-161

Ort / Verlag

De Gruyter

Erscheinungsjahr

2021

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Body fluid cell counting provides valuable information for the diagnosis and treatment of a variety of conditions. Chamber cell count and cellularity analysis by optical microscopy are considered the gold-standard method for cell counting. However, this method has a long turnaround time and limited reproducibility, and requires highly-trained personnel. In the recent decades, specific modes have been developed for the analysis of body fluids. These modes, which perform automated cell counting, are incorporated into hemocytometers and urine analyzers. These innovations have been rapidly incorporated into routine laboratory practice. At present, a variety of analyzers are available that enable automated cell counting for body fluids. Nevertheless, these analyzers have some limitations and can only be operated by highly-qualified laboratory professionals. In this review, we provide an overview of the most relevant automated cell counters currently available for body fluids, the interpretation of the parameters measured by these analyzers, their main analytical features, and the role of optical microscopy as automated cell counters gain ground.