Details

Autor(en) / Beteiligte

• Thompson, Luke R.
• Sanders, Jon G.
• McDonald, Daniel
• Amir, Amnon
• Ladau, Joshua
• Locey, Kenneth J.
• Prill, Robert J.
• Tripathi, Anupriya
• Gibbons, Sean M.
• Ackermann, Gail
• Navas-Molina, Jose A.
• Janssen, Stefan
• Kopylova, Evguenia
• Vázquez-Baeza, Yoshiki
• González, Antonio
• Morton, James T.
• Mirarab, Siavash
• Zech Xu, Zhenjiang
• Jiang, Lingjing
• Haroon, Mohamed F.
• Kanbar, Jad
• Zhu, Qiyun
• Jin Song, Se
• Kosciolek, Tomasz
• Bokulich, Nicholas A.
• Lefler, Joshua
• Brislawn, Colin J.
• Humphrey, Gregory
• Owens, Sarah M.
• Hampton-Marcell, Jarrad
• Berg-Lyons, Donna
• McKenzie, Valerie
• Fierer, Noah
• Fuhrman, Jed A.
• Clauset, Aaron
• Stevens, Rick L.
• Shade, Ashley
• Pollard, Katherine S.
• Goodwin, Kelly D.
• Jansson, Janet K.
• Gilbert, Jack A.
• Knight, Rob

Titel

A communal catalogue reveals Earth’s multiscale microbial diversity

Ist Teil von

• Nature (London), 2017-11, Vol.551 (7681), p.457-463

Ort / Verlag

London: Nature Publishing Group UK

Erscheinungsjahr

2017

Quelle

MEDLINE

Beschreibungen/Notizen

• Our growing awareness of the microbial world’s importance and diversity contrasts starkly with our limited understanding of its fundamental structure. Despite recent advances in DNA sequencing, a lack of standardized protocols and common analytical frameworks impedes comparisons among studies, hindering the development of global inferences about microbial life on Earth. Here we present a meta-analysis of microbial community samples collected by hundreds of researchers for the Earth Microbiome Project. Coordinated protocols and new analytical methods, particularly the use of exact sequences instead of clustered operational taxonomic units, enable bacterial and archaeal ribosomal RNA gene sequences to be followed across multiple studies and allow us to explore patterns of diversity at an unprecedented scale. The result is both a reference database giving global context to DNA sequence data and a framework for incorporating data from future studies, fostering increasingly complete characterization of Earth’s microbial diversity. As phase 1 of the Earth Microbiome Project, analysis of 16S ribosomal RNA sequences from more than 27,000 environmental samples delivers a global picture of the basic structure and drivers of microbial distribution. Earth's microbial diversity In this meta-analysis of studies from the Earth Microbiome Project, Luke Thompson et al . have developed a standardized collection, curation and analysis pipeline to examine 16S ribosomal RNA (rRNA) tag sequences of more than 27,000 samples (representing soil, water, animal-associated and plant-associated habitats), providing global context for the basic structure and drivers of bacterial and archaeal distribution. The work not only provides an important reference database and framework for future studies in microbial ecology, but also reveals patterns in community composition as well as the global distribution of particular organisms. These findings provide a deeper understanding of dispersal and niche colonization.