Details

Autor(en) / Beteiligte

• Suharno, D
• Muhilal
• Karyadi, D
• West, C.E
• Hautvast, J.G.A.J

Titel

Supplementation with vitamin A and iron for nutritional anaemia in pregnant women in West Java, Indonesia

Ist Teil von

• The Lancet (British edition), 1993-11, Vol.342 (8883), p.1325-1328

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

1993

Link zum Volltext

Quelle

Psychology & Behavioral Sciences Collection

Beschreibungen/Notizen

• Nutritional anaemia, thought to be caused by iron deficiency, affects 50-70% of pregnant women in the developing world. The influence of vitamin A and iron supplementation was studied in anaemic pregnant women in West Java, in a randomised, double-masked, placebo-controlled field trial. 251 women aged 17-35 years, parity 0-4, gestation 16-24 weeks, and haemoglobin between 80 and 109 g/L were randomly allocated to four groups: vitamin A (2·4 mg retinol) and placebo iron tablets; iron (60 mg elemental iron) and placebo vitamin A; vitamin A and iron; or both placebos, all daily for 8 weeks. Maximum haemoglobin was achieved with both vitamin A and iron supplementation (12·78 g/L, 95% Cl 10·86 to 14·70), with one-third of the response attributable to vitamin A(3·68 g/L, 2·03 to 5·33) and two-thirds to iron (7·71 g/L, 5·97 to 9·45). After supplementation, the proportion of women who became non-anaemic was 35% in the vitamin-A- supplemented group, 68% in the iron-supplemented group, 97% in the group supplemented with both, and 16% in the placebo group. Improvement in vitamin A status may contribute to the control of anaemic pregnant women.