Details

Autor(en) / Beteiligte

• Querci, M
• van der Vlugt, R
• Goldbach, R
• Salazar, L. F

Titel

RNA sequence of potato virus X strain HB

Ist Teil von

• Journal of general virology, 1993-10, Vol.74 (10), p.2251-2255

Ort / Verlag

Reading: Soc General Microbiol

Erscheinungsjahr

1993

Quelle

MEDLINE

Beschreibungen/Notizen

• 1 The International Potato Center, Apartado 5969, Lima, Peru and 2 Department of Virology, Binnenhaven 11, 6709 PD Wageningen, The Netherlands The genomic RNA of the potato virus X (PVX) strain HB, isolated in Bolivia and able to overcome all known resistance genes, has been cloned and sequenced. The PVX HB RNA sequence is 6432 nucleotides long and contains, similarly to the RNAs of other PVX strains, five open reading frames encoding proteins of M r s 165·1K, 24·5K, 12·4K, 7·6K and 25·1K (coat protein), respectively. Multiple amino acid sequence alignments of the coat proteins of four PVX strains identified eight amino acid residues unique for PVX HB . Structural prediction comparisons of the coat proteins of PVX HB and of the other strains suggest a general structural similarity. However, two of the eight amino acid residues unique for strain HB gave rise to a change in the predicted coat protein structure, suggesting a possible involvement in the resistance-breaking activity of PVX HB . Received 26 January 1993; accepted 8 June 1993.