Details

Autor(en) / Beteiligte

• Spiller, Robert E
• Colombo, Christopher J
• Lindholm, Phillip C
• Kwon, James

Titel

Urea(lly) Got Me: An Uncommon Etiology of Peripartum Liver Failure

Ist Teil von

• ACG case reports journal, 2022-05, Vol.9 (5), p.e00780

Ort / Verlag

United States: Wolters Kluwer

Erscheinungsjahr

2022

Link zum Volltext

Quelle

EZB-FREE-00999 freely available EZB journals

Beschreibungen/Notizen

• A 23-year-old woman presented 4 days postpartum for agitation and confusion, with initial evaluation consistent with acute fatty liver of pregnancy (AFLP). Later in her course, an amino acid panel was highly suggestive of citrullinemia type 1. She was started on arginine supplementation and glycerol phenylbutyrate and evaluated for a liver transplant. After starting the medication and diet modification, her liver failure resolved, and she was safely discharged. Urea cycle disorders may mimic AFLP with liver enzyme elevation, delirium, and hyperammonemia, but unlike AFLP, patients with urea cycle disorders will typically not recover without dietary modifications and/or medication.