Details

Autor(en) / Beteiligte

• Mendoza-Zubieta, Victoria
• Gonzalez-Villaseñor, Gloria A
• Vargas-Ortega, Guadalupe
• Gonzalez, Baldomero
• Ramirez-Renteria, Claudia
• Mercado, Moises
• Molina-Ayala, Mario A
• Ferreira-Hermosillo, Aldo

Titel

High prevalence of metabolic syndrome in a mestizo group of adult patients with primary hyperparathyroidism (PHPT)

Ist Teil von

• BMC endocrine disorders, 2015-04, Vol.15 (1), p.16-16, Article 16

Ort / Verlag

England: BioMed Central Ltd

Erscheinungsjahr

2015

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Primary hyperparathyroidism (PHPT) and metabolic syndrome (MS) have been independently related to cardiovascular morbidities, however this association is still controversial. Mexican population has a high prevalence of metabolic syndrome, however its frequency seems to be even higher than expected in patients with PHPT. We retrospectively reviewed the charts of patients that underwent parathyroidectomy for PHPT in a referral center and used the criteria from the National Cholesterol Educational Program (NCEP)/Adult Treatment Panel III (ATP III) to define MS before surgery. We compared the characteristics between the patients with and without MS. 60 patients were analyzed, 77% were female and 72% had a single parathyroid adenoma. MS was present in 59% of the patients, this group was significantly older (57 vs. 48 years, p = 0.01) and they had lower iPTH (115 vs. 161 ng/ml, p = 0.017). Other parameters did not show differences. MS is frequent in our population diagnosed with primary hyperparathyroidism, adverse cardiovascular parameters are common and significant differences in calcium metabolism compared to the non-MS group are present.