Science (American Association for the Advancement of Science), 2021-04, Vol.372 (6539), p.254
2021
Details
- Autor(en) / Beteiligte
- Titel
- Diversity and functional landscapes in the microbiota of animals in the wild
- Ist Teil von
- Science (American Association for the Advancement of Science), 2021-04, Vol.372 (6539), p.254
- Ort / Verlag
- United States: American Association for the Advancement of Science
- Erscheinungsjahr
- 2021
- Link zum Volltext
- Quelle
- American Association for the Advancement of Science
- Beschreibungen/Notizen
- Animals in the wild are able to subsist on pathogen-infected and poisonous food and show immunity to various diseases. These may be due to their microbiota, yet we have a poor understanding of animal microbial diversity and function. We used metagenomics to analyze the gut microbiota of more than 180 species in the wild, covering diverse classes, feeding behaviors, geographies, and traits. Using de novo metagenome assembly, we constructed and functionally annotated a database of more than 5000 genomes, comprising 1209 bacterial species of which 75% are unknown. The microbial composition, diversity, and functional content exhibit associations with animal taxonomy, diet, activity, social structure, and life span. We identify the gut microbiota of wild animals as a largely untapped resource for the discovery of therapeutics and biotechnology applications.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0036-8075eISSN: 1095-9203DOI: 10.1126/science.abb5352Titel-ID: cdi_proquest_journals_2505403415
- Format
- –
- Schlagworte
- Analysis, Animal species, Animals, Animals, Wild - classification, Animals, Wild - microbiology, Animals, Wild - physiology, Antibiotics, Assembly, Asymptotes, Bacteria, Bacteria - classification, Bacteria - genetics, Bacteria - isolation & purification, Bacterial Toxins - metabolism, Behavior, Animal, Biodiversity, Bioluminescence, Biotechnology, Composition, Construction, Continents, COVID-19, Databases, Nucleic Acid, Diet, Diseases, Ecosystem, Enzymes, Falkland Islands, Feces - microbiology, Feeding behavior, Food, Functionals, Gastrointestinal Microbiome, Genome, Bacterial, Genomes, Host Microbial Interactions, Human populations, Immunity, Immunomodulators, Israel, Madagascar, Mapping, Meat, Metagenome, Metagenomics, Microbiota, Microbiota (Symbiotic organisms), Microorganisms, Pandemics, Pathogens, Peptide Hydrolases - genetics, Peptide Hydrolases - metabolism, Phylogeny, Poisonous species, Queensland, Sampling, Social conditions, Social Structure, Taxonomy, Toxins, Uganda, Wildlife, Wildlife conservation, Wildlife habitats