Details

Autor(en) / Beteiligte

• Noor Dina Muhd Noor
• Matsuura, Hiroaki
• Nishikawa, Koji
• Hulin Tai
• Hirota, Shun
• Kim, Jaehyun
• Kang, Jiyoung
• Tateno, Masaru
• Yoon, Ki-Seok
• Ogo, Seiji
• Kubota, Shintaro
• Shomura, Yasuhito
• Higuchi, Yoshiki

Titel

Redox-dependent conformational changes of a proximal [4Fe–4S] cluster in Hyb-type [NiFe]-hydrogenase to protect the active site from O2

Ist Teil von

• Chemical communications (Cambridge, England), 2018, Vol.54 (87), p.12385-12388

Ort / Verlag

Cambridge: Royal Society of Chemistry

Erscheinungsjahr

2018

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Citrobacter sp. S-77 [NiFe]-hydrogenase harbors a standard [4Fe–4S] cluster proximal to the Ni–Fe active site. The presence of relocatable water molecules and a flexible aspartate enables the [4Fe–4S] to display redox-dependent conformational changes. These structural features are proposed to be the key aspects that protect the active site from O2 attack.