Nature nanotechnology, 2019-07, Vol.14 (7), p.645-657
2019
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- Autor(en) / Beteiligte
- Titel
- An atlas of nano-enabled neural interfaces
- Ist Teil von
- Nature nanotechnology, 2019-07, Vol.14 (7), p.645-657
- Ort / Verlag
- England: Nature Publishing Group
- Erscheinungsjahr
- 2019
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Advances in microscopy and molecular strategies have allowed researchers to gain insight into the intricate organization of the mammalian brain and the roles that neurons play in processing information. Despite vast progress, therapeutic strategies for neurological disorders remain limited, owing to a lack of biomaterials for sensing and modulating neuronal signalling in vivo. Therefore, there is a pressing need for developing material-based tools that can form seamless biointerfaces and interrogate the brain with unprecedented resolution. In this Review, we discuss important considerations in material design and implementation, highlight recent breakthroughs in neural sensing and modulation, and propose future directions in neurotechnology research. Our goal is to create an atlas for nano-enabled neural interfaces and to demonstrate how emerging nanotechnologies can interrogate neural systems spanning multiple biological length scales.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1748-3387eISSN: 1748-3395DOI: 10.1038/s41565-019-0487-xTitel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6800006
- Format
- –
- Schlagworte
- Animals, Biocompatible Materials - chemistry, Biomaterials, Biomedical materials, Brain, Brain - cytology, Brain architecture, Brain research, Electrodes, Energy, Equipment Design, Humans, Information processing, Interfaces, Membranes, Microscopy, Nanostructures - chemistry, Nanotechnology, Nanotechnology - instrumentation, Nanotechnology - methods, Nervous system, Neurological diseases, Neurological disorders, Neurons, Neurons - cytology, Neurosciences, Questioning, Signal transduction, Transplants & implants