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Bu çalışmamızda meme kanserinin cinsel fonksiyonlar üzerine etkisini, bir sorgulama formu kullanarak değerlendirilmesi amaçlandı. Çalışmadan en az bir yıl öncesinde tedavileri (modifiye radikal mastektomi + kemoterapi + radyoterapi) tamamlanmış, premenapozal dönemde ve evli 17 meme kanserli hasta ve 20 sağlıklı kontrol birey çalışmaya alındı. Cinsel işlev bozukluğuna neden olabilecek ilave rahatsızlığı olanlar çalışmadan çıkarıldı. Cinsel istek, uyarılma, orgazm, genel cinsel doyum ve cinsel ağrı olarak tanımlanan cinsel fonksiyonlar, kadın cinsel fonksiyon indeksi ile değerlendirildi, istatistik analizlerde t-testi kullanıldı. Hastalardaki cinsel fonksiyon alan skorları, kontrollere oranla istatistiksel olarak düşük olup sırasıyla, cinsel istekte 1.64±0.92, 3.05±0.63 (p<0.001); uyarılmada 2.20±1.25, 3.20±1.10 (p<0.001); orgazmda 2.4711.23, 3.65±1.04 (p=0.003); doyumda 2.79±1.28, 3.60±0.99 (p=0.039) ve ağrıda 2.3211.93, 3.97±1.00 (p=0.002) şeklinde gerçekleşti. Hastalıklı meme ve/veya mastektominin cinsel beden algısını olumsuz yönde etkilemesi, kemoterapi, radyoterapi ve endokrin tedavi gibi ilave tedavilerin hormonal denge ve genel sağlık durumunu bozması ile meme kanserinin kadında cinsel fonksiyon bozukluğuna neden olduğu kabul edilmektedir. Meme kanserli hastalarda cinsel fonksiyonların sorgulanması, olası bozukluğu ortaya çıkaracak ve yardım isteyenlere uygun çözümler sunma olanağı verecektir.
Introduction: Breast cancer is one of the most threatening health problems of the females for thousands of years with a rate of 30%, and the first one among all female malignancies and has increasing prevalence. Quality of life and sexual function parameters of the patients can quite limit due to the fear of death, loss of body image, negative effects of hormonotherapy, chemotherapy and radiotherapy. We aimed to evaluate the effects of the breast cancer and specific treatment modalities on the female sexual functions using a
self-administered questionnaire. Patients and Methods: Seventeen premenopausal and married patients with breast cancer that their treatments (modified radical mastectomy + chemotherapy + radiotherapy) had been completed at least one year ago, and 20 healthy women as control group were included in the study. The patients with additional pathologies to be caused sexual dysfunction were excluded from this study. Sexual functions described as desire, arousal, orgasm, satisfaction and pain during sexual activity were evaluated with Index of Female Sexual Function (IFSF). All values were expressed as the mean plus minus standard deviation (SD). The groups were compared by using independent
t-test. Significance was defined as p<0.05. Statistical tests were performed by using the SPSS 10.0 for Windows statistical package. Results: Seventeen of 23 patients who were given a self-administered questionnaire accepted to participate hi the study. The mean age of study group was 37.88±7.07 (ranged from 28 to 49 years) and the mean age of control group was 36.6015.83 (ranged from 23 to 45 years). The mean ages of two groups were not different statistically (p= 0.550). The mean follow-up time was 21.50±4.33 months. The values of sexual function score were statistically lower in patients than those of the controls for desire (1.64±0.92 vs 3.05±0.63, p<0.001), arousal (2.20±1.25 vs 3.20±1.10, p<0.001), orgasm (2.47±1.23 vs 3.65±1.04, p=0.003), satisfaction (2.79±1.28 vs 3.60±0.99, p=0.039) and pain (2.32±1.93 vs 3.97±1.00, p=0.002). Conclusion: It has been considered that the breast cancer can cause sexual dysfunction in females because diseased breast and/or mastectomy can poorly effect the perception of sexual body image, and additional therapies such as chemotherapy, radiotherapy and endocrine therapy can change the hormonal and general health status as well. It has been concluded that querying the sexual functions in females with breast cancer can expose the probable sexual dysfunction, and can; lead to offer proper solutions for the willing subjects.